GPR35 (3rd cytopl. dom.) Rabbit Polyclonal Antibody
Specifications
| Product Data | |
| Application | IF, IHC |
|---|---|
| Recommended Dilution | Immunocytochemistry. Immunohistochemistry on Paraffin Sections: 5 - 9 µg/ml. |
| Reactivity | Human |
| Antibody Host | Rabbit |
| Clonality | Polyclonal |
| Immunogen | Synthetic 19 amino acid peptide from 3rd cytoplasmic domain of human GPR35 |
| Specificity | Reacts with G Protein-Coupled Receptor GPR35 (family: GPCR, subfamily: Orphan-A) |
| Buffer | PBS containing 0.09% sodium azide State: Aff - Purified State: Liquid Ig fraction |
| Concentration | lot specific |
| Purification | Peptide immunogen affinity column |
| Conjugation | Unconjugated |
| Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C to -70°C for longer. Avoid repeated freezing and thawing. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Gene Name | G protein-coupled receptor 35 |
| Database Link | |
| Background | GPR35 is an Orphan-A GPCR with an unknown ligand. GPR35 expression was reported only in rat intestine by Northern hybridization; however, another study showed that GPR35 is expressed widely, including pancreatic islets and skeletal muscle, with higher levels in adult lung, small intestine, colon, and stomach. ESTs have been isolated from human fetal lung/testis/B-cell, colon (normal, cancer, and Crohn's disease), breast cancer, pancreatic cancer, and leukemia libraries. |
| Synonyms | G-protein coupled receptor 35, Kynurenic acid receptor, KYNA receptor |
| Reference Data | |
| Protein Categories | Chemokines, GPCR, Membrane Proteins |
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