Endo G (ENDOG) Rabbit Polyclonal Antibody
Specifications
| Product Data | |
| Application | IHC, WB |
|---|---|
| Recommended Dilution | Western blot: 1 µg/ml - 2 µg/ml; this antibody detects a band of approximately 35kDa in HepG2 and 3T3 cell lysates. Immunohistochemistry on paraffin sections: 15 µg/ml; Sodium citrate buffer pH6.0 is recommended for this purpose. Recommended Positive Control: Human pancreas. |
| Reactivity | Human, Mouse, Rat |
| Antibody Host | Rabbit |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide corresponding to amino acids 55 - 70 of endonuclease G. |
| Specificity | This antibody recognises endonuclease G (endoG). |
| Buffer | PBS containing 0.09% Sodium Azide State: Purified State: Liquid purified IgG |
| Concentration | lot specific |
| Purification | Affinity chromatography |
| Conjugation | Unconjugated |
| Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Gene Name | endonuclease G |
| Database Link | |
| Background | Endonuclease G is a mitochondrion-specific nuclease that translocates to the nucleus and cleaves chromatin DNA during apoptosis. endoG is reported to act independently of caspases and may represent a caspase independent apoptotic pathway initiated from the mitochondria. |
| Synonyms | ENDOG |
| Reference Data | |
| Protein Categories | Intracellular Proteins |
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