CD44 Mouse Monoclonal Antibody [Clone ID: CVS18]

SKU
SM502F
CD44 mouse monoclonal antibody, clone CVS18, FITC, Purified
  $785.00
5 Days*
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Specifications
Specifications
Product Data
Clone Name CVS18
Application FC
Recommended Dilution Flow cytometry: Neat - 1/10, use 10µl of the suggested working dilution to label 106 cells in 100µl.
Reactivity Equine
Antibody Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Equine leucocytes
Specificity Clone CVS18 antibody detects equine CD44 and may be used as a pan equine leucocyte marker.
Buffer 0.09% Sodium azide and 1% BSA
Label: FITC
State: Purified
State: Liquid purified IgG
Label: Fluorescein Isothiocyanate Isomer 1
Concentration lot specific
Purification Affinity chromatography on Protein G
Conjugation FITC
Storage Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
This product is photosensitive and should be protected from light.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Shipping Blue Ice
Database Link
Background CD44 is a type 1 transmembrane glycoprotein also known as Phagocytic Glycoprotein 1 (pgp 1) and HCAM. CD44 is the receptor for hyaluronate and exists as a large number of different isoforms due to alternative RNA splicing. The major isoform expressed on lymphocytes, myeloid cells, and erythrocytes is a glycosylated type 1 transmembrane protein. Other isoforms contain glycosaminoglycans and are expressed on hematopoietic and non hematopoietic cells. CD44 is involved in adhesion of leukocytes to endothelial cells, stromal cells, and the extracellular matrix.
Synonyms LHR, MDU2, MDU3, MIC4, CDw44, Epican, ECMR-III, HUTCH-I, Heparan sulfate proteoglycan, Hermes antigen, Hyaluronate receptor, PGP-1
Reference Data
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Documents
Resources

file-alt Citations

In search for cross-reactivity to immunophenotype equine mesenchymal stromal cells by multicolor flow cytometry
De Schauwer, Piepers, Van de Walle et al
Cytometry A (2012) 81 (4), 312-23 DOI: 10.1002/cyto.a.22026
Cited by 112
AI Summary: In this study, OriGene’s mouse anti-human CD44 antibody (clone 156-3C11, Cat# TA803574) was used to assess cross-reactivity and immunophenotype equine mesenchymal stromal cells by flow cytometry, contributing to the identification of CD44 as a positive marker in the proposed nine-marker panel.
Comparative Analysis of the Immunomodulatory Properties of Equine Adult-Derived Mesenchymal Stem Cells()
Carrade, Lame, Kent et al
Cell Med (2012) 4 (1), 1-11 DOI: 10.3727/215517912X647217
Temporal analysis of equine bone marrow aspirate during establishment of putative mesenchymal progenitor cell populations
Radcliffe, Flaminio, Fortier
Stem Cells Dev (2010) 19 (2), 269-82 DOI: 10.1089/scd.2009.0091
Cited by 120
AI Summary: OriGene products contributed to this study by providing specific gene expression assay reagents, including equine CD44, CD29, CD90, CD11a/CD18, and CD45RB RT-qPCR primers, which enabled accurate measurement of temporal gene expression changes during mesenchymal progenitor cell culture establishment.
Showing 1-3 of 3 papers.
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