CD41 (ITGA2B) Mouse Monoclonal Antibody [Clone ID: MEM-06]
$450.00
2 Weeks*
Specifications
| Product Data | |
| Clone Name | MEM-06 |
|---|---|
| Application | FC |
| Recommended Dilution | Flow Cytometry analysis of human blood cells using 20 µl reagent/100 µl of whole blood or 106 cells in a suspension. |
| Reactivity | Human |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Leukocytes of patient suffering from LGL-type leukaemia |
| Specificity | This antibody reacts with CD41 (GPIIb), a transmembrane glycoprotein (integrin family) composed of two chains GPIIbalpha (heavy chain: 120 kDa) and GPIIbbeta (light chain: 23 kDa). CD41 is mainly expressed on platelets and megakaryocytes. |
| Buffer | Phosphate buffered saline (PBS) containing 15 mM Sodium Azide as preservative Label: PE State: Liquid purified Ig fraction Label: Conjugated with R-Phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. |
| Conjugation | PE |
| Storage | Store the antibody at 2-8°C. DO NOT FREEZE! This product is photosensitive and should be protected from light. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Gene Name | integrin subunit alpha 2b |
| Database Link | |
| Background | CD41 (platelet glycoprotein IIb) is composed of two subunits (120 kDa a, a and 23 kDa b, b) that interact with CD61 in the presence of calcium to form a functional adhesive protein receptor. Upon blood vessel damage, this receptor binds to a variety of proteins including von Willebrand factor, fibrinogen, fibronectin and vitronectin. CD41 is mainly expressed on megakaryocyte-platelet lineage, but generally belongs to the antigens that are expressed during early stages of hematopoietic differentiation. |
| Synonyms | Integrin alpha-IIb, GP2B, ITGAB, GPalpha IIb |
| Reference Data | |
| Protein Categories | Cardiovascular diseases, CD Markers, Intracellular Proteins, Membrane Proteins |
Reviews
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Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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