Icam1 Mouse Monoclonal Antibody [Clone ID: 1A29]
Specifications
| Product Data | |
| Clone Name | 1A29 |
|---|---|
| Application | FC |
| Recommended Dilution | Flow Cytometry: Use 10 µl of neat antibody to label 10e6 cells in 100 µl. |
| Reactivity | Rat |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Rat Ax cells (a rat HEV derived cell line). |
| Specificity | This antibody recognizes the CD54 cell surface antigen, also known as intercellular adhesion molecule-1 (ICAM-1). Recent studies suggest that cross-linking of ICAM-1 using clone 1A29 induces calcium signalling. Functionally 1A29 inhibits homotypic aggregation of PHA blasts. We recommend SM286LE for this use. |
| Buffer | PBS, pH 7.2, containing 1% BSA as stabiliser and 0.09% Sodium Azide as preservative. Label: FITC State: Liquid purified IgG fraction Label: Fluorescein Isothiocyanate Isomer 1 |
| Concentration | lot specific |
| Purification | Affinity Chromatography on Protein G |
| Conjugation | FITC |
| Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Gene Name | intercellular adhesion molecule 1 |
| Database Link | |
| Background | CD54 cell surface antigen, also known as the intercellular adhesion molecule-1 (ICAM-1), is a 90 kD adhesion molecule belonging to the immunoglobulin superfamily. This is a cell surface ligand of the lymphocyte integrin, LFA-1 and is known to play an important role in various cell-cell interactions in the immune system. |
| Synonyms | ICAM-1 |
| Reference Data | |
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