OVAL Mouse Monoclonal Antibody [Clone ID: 2C6]
Specifications
| Product Data | |
| Clone Name | 2C6 |
|---|---|
| Application | ELISA |
| Recommended Dilution | ELISA (1/1000-1/5000). The antibody is suitable for use as a Mouse IgE standard in ELISA assays. |
| Reactivity | Chicken |
| Antibody Host | Mouse |
| Isotype | IgE |
| Clonality | Monoclonal |
| Immunogen | Ovalbumin. |
| Specificity | This Mouse monoclonal antibody specifically recognizes Ovalbumin (OVA). |
| Buffer | PBS State: Purified State: Liquid purified IgE fraction prepared from Tissue Culture Supernatant Preservative: 0.09% Sodium Azide |
| Concentration | lot specific |
| Conjugation | Unconjugated |
| Storage | Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Gene Name | ovalbumin (SERPINB14) |
| Database Link | |
| Background | Chicken Ovalbumin is the major protein in the "white" of the egg (and a favorite antigen in immunological research). Egg white contains a variety of proteins including ovalbumin, conalbumin, ovomucoid and lysozyme. It belongs to the serpin family and the Ov serpin subfamily. Ovalbumin can cause an allergic reaction in humans. Ovalbumin has been implicated in the development of the egg shell. Immunohistochemistry revealed that ovalbumin is found only in the mammillary bodies of decalcified shell, and is not distributed throughout the shell matrix. These results indicate that ovalbumin is present during the initial phase of shell formation and becomes incorporated into the protein matrix of the mammillary bodies. However, it is not yet clear whether ovalbumin at this site plays a specific role in shell mineralisation. |
| Synonyms | SERPINB14, Egg albumin, Plakalbumin, Allergen Gal d II |
| Reference Data | |
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Citations
Neuronal Fc-epsilon receptor I contributes to antigen-evoked pruritus in a murine model of ocular allergy
Liu, Xu, Chen et al
Brain Behav Immun (2017) 61, 165-175 DOI: 10.1016/j.bbi.2016.11.017
Liu, Xu, Chen et al
Brain Behav Immun (2017) 61, 165-175 DOI: 10.1016/j.bbi.2016.11.017
Cited by 23
AI Summary: In this study, OriGene's siRNA for FcεRIα was used to specifically block neuronal responses to IgE-immune complex in trigeminal ganglion neurons, demonstrating the role of FcεRI in allergic ocular itch.
Showing 1-1 of 1 papers.
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