CD46 Mouse Monoclonal Antibody [Clone ID: MEM-258]
Specifications
| Product Data | |
| Clone Name | MEM-258 |
|---|---|
| Application | FC |
| Recommended Dilution | Flow cytometry. |
| Reactivity | Human |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | HPB-ALL cell line |
| Specificity | This antibody recognises the CD46 cell surface antigen, a broadly expressed glycoprotein also known as membrane co-factor protein (MCP). |
| Buffer | PBS containing 0.09% Sodium Azide and 1% Bovine Serum Albumin Label: FITC State: Liquid purified IgG fraction Label: Fluorescein Isothiocyanate Isomer 1 |
| Concentration | lot specific |
| Purification | Affinity chromatography on Protein A |
| Conjugation | FITC |
| Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. This product is photosensitive and should be protected from light. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Gene Name | CD46 molecule |
| Database Link | |
| Background | CD46 functions as an inhibitor of complement activation limiting the formation and activity of C3 convertases. CD46 is expressed by all nucleated cells, often as multiple isoforms on the same cells. The molecule is also expressed by sperm and may be important in the process of fertilisation. |
| Synonyms | TLX, MIC10 |
| Reference Data | |
| Protein Categories | ADC Targets, Cardiovascular diseases, CD Markers, Growth Factors, Intracellular Proteins, Membrane Proteins |
Reviews
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