CD71 (TFRC) Mouse Monoclonal Antibody [Clone ID: DF1513]
Specifications
| Product Data | |
| Clone Name | DF1513 |
|---|---|
| Application | FC |
| Recommended Dilution | Flow Cytometry: Use 10 µl of 1/10-1/25 diluted antibody to label 10e6 cells in 100 µl. |
| Reactivity | Human, Monkey |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | KG1 cell line. |
| Specificity | This antibody recognizes the CD71 cell surface antigen, a 190 kD homodimeric glycoprotein expressed by proliferating cells. CD71 acts as Receptor for Transferrin. |
| Buffer | PBS without preservatives State: Low Endotoxin State: Liquid purified IgG fraction |
| Concentration | lot specific |
| Purification | Affinity Chromatography on Protein G |
| Conjugation | Unconjugated |
| Storage | Store the antibody undiluted at -20°C. Avoid repeated freezing and thawing. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Gene Name | transferrin receptor |
| Database Link | |
| Background | The transferrin receptor has been structurally characterized as a sulfide bound dimer of identical glycoprotein subunits of 95 kDa. The transferrin receptor is not present on resting blood lymphocytes. On PBL, the receptor appears after activation. The expression of transferrin receptor is coordinately regulated with cell growth. Present on T and B cell lines. The soluble (or serum) transferrin receptor (sTfR) is a circulating truncated form of the membrane receptor protein; it is an 85 kDa glycoprotein forming in serum a 320 kDa complex with diferric transferrin.The most important clinical use of the sTfR determination is in the differential diagnosis between iron deficiency anaemia and the anaemia of chronic disease. |
| Synonyms | TfR1, p90, Transferrin receptor protein 1 |
| Note | Low Endotoxin: < 0.01 EU/µg |
| Reference Data | |
| Protein Categories | ADC Targets, CD Markers, Enzyme: Peptidases, Immune system diseases, Intracellular Proteins, Membrane Proteins, Secreated Proteins |
| Protein Families | Druggable Genome, ES Cell Differentiation/IPS, Protease, Secreted Protein, Transmembrane |
| Protein Pathways | Endocytosis, Hematopoietic cell lineage |
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