Ifng Mouse Monoclonal Antibody [Clone ID: DB1]

CAT#: SM098PS

Ifng mouse monoclonal antibody, clone DB1, Purified

Specifications

Product Data

• Clone Name: DB1
• Applications: ELISA, IHC
• Recommended Dilution: ELISA: 10µg/ml - 100µg/ml.
  Immunohistochemistry on frozen sections.
• Reactivities: Mouse, Rat
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Recombinant rat IFN gamma.
• Specificity: This antibody reacts with IFN-gamma. Clone DB-1 exhibits high affinity binding to the natural and recombinant forms and effectively neutralises the anti viral activity of IFN-gamma. It also blocks the induction of Ia antigen expression on murine keratinocytes. There is no cross-reaction with rodent IFN-alpha or IFN-beta or with human interferons. Clone DB-1 has also been reported for use in neutralising studies. MCA1301XZ is recommended for this
  purpose.
• Formulation: PBS containing 125mM trehalose and 0.09% Sodium Azide
  State: Purified
  State: Liquid purified IgG
• Concentration: lot specific
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: interferon gamma
• Database Link:
  Entrez Gene 15978 Mouse
  UniProt ID P01580
• Background: Interferon gamma is mainly produced by T lymphocytes and NK cells. It is a pleiotropic cytokine involved in the regulation of nearly all phases of immune and inflammatory responses,including the activation, growth and differentiation of T cell, B cells, macrophages, NK cells and other cell types such as endothelial cells and fibroblasts. It has weak antiviral and antiproliferative activity, and poteniates the antiviral and anti tumor effects of IFN alpha / beta (type I interferon). It is upregulated by IL2, FGF basic, EGF and downregulated by vitamin D3 or DMN. Labile at pH 2.
• Synonyms: IFN-gamma, gamma IFN