Ifng Mouse Monoclonal Antibody [Clone ID: DB1]
Specifications
| Product Data | |
| Clone Name | DB1 |
|---|---|
| Application | ELISA, IHC |
| Recommended Dilution | ELISA: 10µg/ml - 100µg/ml. Immunohistochemistry on frozen sections. |
| Reactivity | Mouse, Rat |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Recombinant rat IFN gamma. |
| Specificity | This antibody reacts with IFN-gamma. Clone DB-1 exhibits high affinity binding to the natural and recombinant forms and effectively neutralises the anti viral activity of IFN-gamma. It also blocks the induction of Ia antigen expression on murine keratinocytes. There is no cross-reaction with rodent IFN-alpha or IFN-beta or with human interferons. Clone DB-1 has also been reported for use in neutralising studies. MCA1301XZ is recommended for this purpose. |
| Buffer | PBS containing 125mM trehalose and 0.09% Sodium Azide State: Purified State: Liquid purified IgG |
| Concentration | lot specific |
| Conjugation | Unconjugated |
| Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Gene Name | interferon gamma |
| Database Link | |
| Background | Interferon gamma is mainly produced by T lymphocytes and NK cells. It is a pleiotropic cytokine involved in the regulation of nearly all phases of immune and inflammatory responses,including the activation, growth and differentiation of T cell, B cells, macrophages, NK cells and other cell types such as endothelial cells and fibroblasts. It has weak antiviral and antiproliferative activity, and poteniates the antiviral and anti tumor effects of IFN alpha / beta (type I interferon). It is upregulated by IL2, FGF basic, EGF and downregulated by vitamin D3 or DMN. Labile at pH 2. |
| Synonyms | IFN-gamma, gamma IFN |
| Reference Data | |
| Protein Categories | Allergies and autoimmune diseases, Cardiovascular diseases, Chemokines, Cytokines, Secreated Proteins |
Reviews
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Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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