Cd44 Mouse Monoclonal Antibody [Clone ID: 5035-41.1D]
Specifications
| Product Data | |
| Clone Name | 5035-41.1D |
|---|---|
| Application | FC, IP |
| Recommended Dilution | Flow Cytometry: Use 10 µl of 1/50-1/100 diluted antibody to label 10e6 cells in 100 µl. Immunoprecipitation. |
| Reactivity | Mouse |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Spleen cells from B6PL-Ly-2a / Ly-3a B6-Ly-1alpha mice. Spleen cells from immunised mice were fused with cells of the mouse P3-NS1-1-Ag4 myeloma cell line. |
| Specificity | Ly24.2 found on more than 90% bone marrow cells and spleen cells, 56% of thymus cells and 90% of lymph node cells. This antibody recognises the following strains of mice:- C57BL/6, C57BL/10, C57/L, C58A, AKR, 129, SJL, NZB, C3H, CE, CBA/H. |
| Buffer | PBS, pH 7.4 containing 0.09% Sodium Azide as preservative. State: Purified State: Liquid purified IgG fraction. |
| Purification | Affinity Chromatography on Protein G from tissue culture supernatant. |
| Conjugation | Unconjugated |
| Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Gene Name | CD44 antigen |
| Database Link | |
| Background | CD44 is a receptor for hyaluronic acid (HA) and is involved in cell-cell interactions, cell adhesion and migration. CD44 also participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing. CD44 expression may be up-regulated upon some carcinomas, and it has been speculated that this may be related to metastatic potential. |
| Synonyms | LHR, MDU2, MDU3, MIC4, CDw44, Epican, ECMR-III, HUTCH-I, Heparan sulfate proteoglycan, Hermes antigen, Hyaluronate receptor, PGP-1 |
| Reference Data | |
| Protein Categories | ADC Targets, CD Markers, Cytokines, Growth Factors, Intracellular Proteins, Membrane Proteins, Secreated Proteins |
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