Msr1 Rat Monoclonal Antibody [Clone ID: 2F8]

SKU SM029P

Msr1 rat monoclonal antibody, clone 2F8, Purified

Product Data

• Clone Name: 2F8
• Application: ELISA, FC, IHC, IP, WB
• Recommended Dilution: ELISA.; Western blot: This antibody recognizes CD204 in J774 cells under non-reduced conditions only.; Immunoprecipitation.; Immunohistochemistry on Frozen Sections.; Flow Cytometry: Use 10 µl of 1/50-1/100 diluted antibody to label 10⁶ cells in 100 µl.
• Reactivity: Mouse, Porcine
• Antibody Host: Rat
• Isotype: IgG2b
• Clonality: Monoclonal
• Immunogen: Raw 264 cell line.
• Specificity: This antibody recognizes the Murine scavenger receptor class A (SRA), type I and II, also known as CD204.; Clone 2F8 inhibits the uptake of acetylated low-density lipoproteins and also inhibits divalent cation independent adhesion. We recommend the use of SM029LE for this purpose.; Recent research shows that clone 2F8 recognizes an epitope within SRA that is polymorphic in the SRA from C57BL/6 mice. Clone 2F8 is therefore unsuitable for use with the C57BL/6 Mouse strain.
• Buffer: PBS, pH 7.4; State: Purified; State: Liquid purified IgG fraction; Preservative: 0.09% Sodium Azide
• Concentration: lot specific
• Purification: Affinity Chromatography on Protein G
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.; Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Shipping: Blue Ice
• Gene Name: macrophage scavenger receptor 1
• Database Link:
  P30204
• Background: CD204 is expressed by tissue macrophages and functions both as an endocytic receptor for lipoproteins and as an adhesion receptor for macrophages binding to ligand rich tissues e.g. atherosclerotic lesions.
• Synonyms: MSR1, SCARA1

Reference Data