TIE2 (TEK) Mouse Monoclonal Antibody [Clone ID: Cl.16]

SKU
DM3511B
TIE2 (TEK) mouse monoclonal antibody, clone Cl.16, Biotin
  $415.00
2 Weeks*
Bulk/Customize
Specifications
Specifications
Product Data
Clone Name Cl.16
Application ELISA, FC, WB
Recommended Dilution Western Blot.
ELISA: 1-2 µg/ml.
FACS analysis and cell sorting: 2-5 µg/ml.
Reactivity Human
Antibody Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Recombinant human soluble CD202b / TIE-2 protein
Specificity The unconjugated monoclonal antibody will detect native human TIE-2 /TEK in ELISA experiments and on the surface of different human cell types.
Buffer PBS
Label: Biotin
State: Lyophilised purified IgG fraction from culture supernatant
Stabilizer: 50x BSA
Preservative: 0.02% Sodium Azide
Reconstitution Method Restore to a concentration of 0.1-1.0 mg/ml with sterile water. Centrifuge vial prior to opening
Purification Protein G Chromatography
Conjugation Biotin
Storage Store lyophilized at 2-8°C for 6 months or at -20°C long term.
After reconstitution store the antibody undiluted at 2-8°C for one month
or (in aliquots) at -20°C long term.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Shipping Ambient
Gene Name TEK receptor tyrosine kinase
Database Link
Background TIE2 (tyrosine kinase with Ig and EGF homology domains 2) is expressed almost exclusively in endothelial cells in mice, rats and humans. This receptor possesses a unique extracellular domain containing two immunoglobulin like loops separated by three epidermal growth factor like repeats that are connected to three fibronectin type III like repeats. The ligand for the receptor is Angiopoietin 1. Defects in TIE2 are associated with inherited venous malformations; the TIE2 signaling pathway appears to be critical for endothelial cell smooth muscle cell communication in venous morphogenesis.
Synonyms TIE2, TIE-2, Angiopoietin-1 receptor, p140 TEK
Reference Data
Protein Categories CD Markers, Enzyme: Kinases, Growth Factors, Membrane Proteins, Secreated Proteins
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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