TIE2 (TEK) Mouse Monoclonal Antibody [Clone ID: Cl.9]
Specifications
| Product Data | |
| Clone Name | Cl.9 |
|---|---|
| Application | ELISA, FC, IHC, WB |
| Recommended Dilution | Suitable for ELISA (1-15 µg/ml), Western blot (1-2 µg/ml), FACS and cell sorting (2-5 µg/ml). |
| Reactivity | Human |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Recombinant Human soluble extracellular TIE-2. |
| Specificity | This monoclonal antibody will detect native Human TIE-2/tek in ELISA experiments and on the surface of different Human cell types. |
| Buffer | PBS, pH 7.4 without preservatives or stabilizers State: Purified State: Lyophilized purified Ig fraction |
| Reconstitution Method | Restore in sterile water to a concentration of 1.0 mg/ml. |
| Purification | Affinity Chromatography on Protein G |
| Conjugation | Unconjugated |
| Storage | Prior to reconstitution store at 2-8°C. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Ambient |
| Gene Name | TEK receptor tyrosine kinase |
| Database Link | |
| Background | TIE2 (tyrosine kinase with Ig and EGF homology domains 2) is expressed almost exclusively in endothelial cells in mice, rats and humans. This receptor possesses a unique extracellular domain containing two immunoglobulin like loops separated by three epidermal growth factor like repeats that are connected to three fibronectin type III like repeats. The ligand for the receptor is Angiopoietin 1. Defects in TIE2 are associated with inherited venous malformations; the TIE2 signaling pathway appears to be critical for endothelial cell smooth muscle cell communication in venous morphogenesis. |
| Synonyms | TIE2, TIE-2, Angiopoietin-1 receptor, p140 TEK |
| Reference Data | |
| Protein Categories | CD Markers, Enzyme: Kinases, Growth Factors, Membrane Proteins, Secreated Proteins |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Citations
Related Products
- Price:
- Actual Price:
Welcome to OriGene AI!
I'm your AI-powered guide to everything OriGene.
Ask me anything:
- Product specs
- Ordering help
- Technical questions
- How to find exactly what your experiment needs
Prefer a live agent? Connect with us by clicking the green chat icon, as seen in the image below or email our team at custsupport@origene.com.