Fibronectin (FN1) Mouse Monoclonal Antibody [Clone ID: 568]
$650.00
2 Weeks*
Specifications
| Product Data | |
| Clone Name | 568 |
|---|---|
| Application | IHC, IP, R, WB |
| Recommended Dilution | Immunoblotting. Cell preparations. Immunohistochemistry on Frozen Sections. Immunohistochemistry on Paraffin Sections (after microwave treatment). Working Dilutions: 1/5-1/10. Incubation time: 1 h at room temperature. Recommended Positive Control: Human skin, ulcerating tissue. |
| Reactivity | Human |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | High molecular weight proteins secreted by cultivated Human fibroblasts. |
| Specificity | This antibody 568 reacts with the cell binding part of the Fibronectin molecule. Fibronectin seems to play a key role in the tumor cell extracellular matrix during in-vasive tumor growth. Increasing expression of stro-mal fibronectin has been reported during tumor pro-gression. In immunohistochemistry the antibody is reactive with an extracellular matrix glycoprotein in vessels and connective tissue. |
| Buffer | PBS State: Supernatant State: Liquid Culture Supernatant Stabilizer: 1% BSA Preservative: 0.09% Sodium Azide |
| Conjugation | Unconjugated |
| Storage | Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Gene Name | fibronectin 1 |
| Database Link | |
| Background | Fibronectin is a glycoprotein present in a soluble dimeric form in plasma, and in a dimeric or multimeric form at the cell surface and in extracellular matrix. Fibronectin is involved in cell adhesion and migration processes including embryogenesis, wound healing, blood coagulation, host defense, and metastasis. They occur as dimers of two 250 kDa subunits. They have binding domains for bacterial proteins, collagens, heparin-like molecules and fibrin. Cellular fibronectin is widely distributed in the stroma of malignant tumours. |
| Synonyms | FN1, Cold-insoluble globulin, CIG |
| Reference Data | |
| Protein Categories | ADC Targets, Growth Factors, Intracellular Proteins, Secreated Proteins |
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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