MYBPC3 Mouse Monoclonal Antibody [Clone ID: OTI2D8D7]
$620.00
3 Days*
Specifications
| Product Data | |
| Clone Name | OTI2D8D7 |
|---|---|
| Application | ELISA |
| Recommended Dilution | ELISA 1:5000-10000 |
| Reactivity | Human |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Full length human recombinant protein of human MYBPC3（C0-C1） (NP_000247) produced in E.coli. |
| Buffer | Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose) |
| Reconstitution Method | For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific) |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | Unconjugated |
| Shipping | Ambient |
| Predicted Protein Size | 140.8 kDa |
| Gene Name | myosin binding protein C3 |
| Database Link | |
| Background | MYBPC3 encodes the cardiac isoform of myosin-binding protein C. Myosin-binding protein C is a myosin-associated protein found in the cross-bridge-bearing zone (C region) of A bands in striated muscle. MYBPC3, the cardiac isoform, is expressed exclussively in heart muscle. Regulatory phosphorylation of the cardiac isoform in vivo by cAMP-dependent protein kinase (PKA) upon adrenergic stimulation may be linked to modulation of cardiac contraction. Mutations in MYBPC3 are one cause of familial hypertrophic cardiomyopathy. provided by RefSeq, Jul 2008 |
| Synonyms | CMD1MM; CMH4; cMyBP-C; FHC; LVNC10; MYBP-C |
| Reference Data | |
| Protein Categories | Cardiovascular diseases, Intracellular Proteins |
| Protein Families | Druggable Genome |
| Protein Pathways | Dilated cardiomyopathy, Hypertrophic cardiomyopathy (HCM) |
Reviews
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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