NEDD4 Mouse Monoclonal Antibody [Clone ID: OTI7A1]
Specifications
| Product Data | |
| Clone Name | OTI7A1 |
|---|---|
| Application | WB |
| Recommended Dilution | WB 1:500 |
| Reactivity | Human |
| Antibody Host | Mouse |
| Isotype | IgG2a |
| Clonality | Monoclonal |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 160-460 of human NEDD4 (NP_940682) produced in E.coli. |
| Buffer | Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose) |
| Reconstitution Method | For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific) |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Ambient |
| Predicted Protein Size | 140.7 kDa |
| Gene Name | NEDD4 E3 ubiquitin protein ligase |
| Database Link | |
| Background | This gene is the founding member of the NEDD4 family of HECT ubiquitin ligases that function in the ubiquitin proteasome system of protein degradation. The encoded protein contains an N-terminal calcium and phospholipid binding C2 domain followed by multiple tryptophan-rich WW domains and, a C-terminal HECT ubiquitin ligase catalytic domain. It plays critical role in the regulation of a number of membrane receptors, endocytic machinery components and the tumor suppressor PTEN. provided by RefSeq, Jul 2016 |
| Synonyms | NEDD4-1; RPF1 |
| Reference Data | |
| Protein Categories | Growth Factors, Intracellular Proteins |
| Protein Families | Druggable Genome |
| Protein Pathways | Endocytosis, Ubiquitin mediated proteolysis |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other "OTI7A1" antibodies (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| TA812647 | NEDD4 mouse monoclonal antibody,clone OTI7A1 | 100 ul |
$447.00
|
|
| TA812647AM | NEDD4 mouse monoclonal antibody,clone OTI7A1, Biotinylated | 100 ul |
$509.00
|
|
| TA812647BM | NEDD4 mouse monoclonal antibody,clone OTI7A1, HRP conjugated | 100 ul |
$509.00
|
|
| TA812647S | NEDD4 mouse monoclonal antibody,clone OTI7A1 | 30 ul |
$200.00
|
|
Citations
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