COX17 Mouse Monoclonal Antibody [Clone ID: OTI2D7]
Specifications
| Product Data | |
| Clone Name | OTI2D7 |
|---|---|
| Application | IHC, WB |
| Recommended Dilution | WB 1:2000, IHC 1:500 |
| Reactivity | Human, Mouse, Rat |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 2-63 of human COX17 (NP_005685) produced in E.coli. |
| Buffer | Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose) |
| Reconstitution Method | For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific) |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Ambient |
| Gene Name | cytochrome c oxidase copper chaperone COX17 |
| Database Link | |
| Background | Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein which is not a structural subunit, but may be involved in the recruitment of copper to mitochondria for incorporation into the COX apoenzyme. This protein shares 92% amino acid sequence identity with mouse and rat Cox17 proteins. This gene is no longer considered to be a candidate gene for COX deficiency. A pseudogene COX17P has been found on chromosome 13. provided by RefSeq, Jul 2008 |
| Synonyms | MGC104397; MGC117386 |
| Reference Data | |
| Protein Categories | Intracellular Proteins |
| Protein Pathways | Metabolic pathways, Oxidative phosphorylation |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other "OTI2D7" antibodies (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| TA812118 | COX17 mouse monoclonal antibody,clone OTI2D7 | 100 ul |
$447.00
|
|
| TA812118AM | COX17 mouse monoclonal antibody,clone OTI2D7, Biotinylated | 100 ul |
$509.00
|
|
| TA812118BM | COX17 mouse monoclonal antibody,clone OTI2D7, HRP conjugated | 100 ul |
$509.00
|
|
| TA812118S | COX17 mouse monoclonal antibody,clone OTI2D7 | 30 ul |
$200.00
|
|
Citations
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