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CD10 (MME) Mouse Monoclonal Antibody [Clone ID: OTI2A4]

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SKU
CF810614
Carrier-free (BSA/glycerol-free) MME mouse monoclonal antibody,clone OTI2A4
Size:
100 ug
Formulation:
Carrier-free Standard
Conjugation:
Unconjugated
  $620.00
3 Days*
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View other "CD10 or NM_007288" antibodies

Specifications
Specifications
Product Data
Clone Name OTI2A4
Application IHC, WB
Recommended Dilution WB 1:500, IHC 1:500
Reactivity Human, Mouse, Rat
Antibody Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Human recombinant protein fragment corresponding to amino acids 411-750 of human MME (NP_009219) produced in E.coli.
Buffer Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Ambient
Gene Name membrane metalloendopeptidase
Database Link
Background This gene encodes a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL). This protein is present on leukemic cells of pre-B phenotype, which represent 85% of cases of ALL. This protein is not restricted to leukemic cells, however, and is found on a variety of normal tissues. It is a glycoprotein that is particularly abundant in kidney, where it is present on the brush border of proximal tubules and on glomerular epithelium. The protein is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon, enkephalins, substance P, neurotensin, oxytocin, and bradykinin. This gene, which encodes a 100-kD type II transmembrane glycoprotein, exists in a single copy of greater than 45 kb. The 5' untranslated region of this gene is alternatively spliced, resulting in four separate mRNA transcripts. The coding region is not affected by alternative splicing. provided by RefSeq, Jul 2008
Synonyms CALLA; CD10; CMT2T; NEP; SCA43; SFE
Reference Data
Protein Categories CD Markers, Cytokines, Enzyme: Peptidases, Intracellular Proteins, Membrane Proteins, Nervous system: Neurodegenerative diseases
Protein Families Druggable Genome, Protease, Transmembrane
Protein Pathways Alzheimer's disease, Hematopoietic cell lineage, Renin-angiotensin system
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Other "OTI2A4" antibodies (4)
SKU Description Size Price
TA810614 MME mouse monoclonal antibody,clone OTI2A4 100 ul
$447.00
TA810614AM MME mouse monoclonal antibody,clone OTI2A4, Biotinylated 100 ul
$509.00
TA810614BM MME mouse monoclonal antibody,clone OTI2A4, HRP conjugated 100 ul
$509.00
TA810614S MME mouse monoclonal antibody,clone OTI2A4 30 ul
$200.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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