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DIRAS2 Mouse Monoclonal Antibody [Clone ID: OTI8A5]

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SKU
CF809398
Carrier-free (BSA/glycerol-free) DIRAS2 mouse monoclonal antibody,clone OTI8A5
Size:
100 ug
Formulation:
Carrier-free Standard
Conjugation:
Unconjugated
  $620.00
3 Days*
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View other "DIRAS2 or NM_017594" antibodies

Specifications
Specifications
Product Data
Clone Name OTI8A5
Application IHC, WB
Recommended Dilution WB 1:500~2000, IHC 1:150
Reactivity Human, Mouse, Rat
Antibody Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Human recombinant protein fragment corresponding to amino acids 1-196 of human DIRAS2(NP_060064) produced in E.coli.
Buffer Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Ambient
Predicted Protein Size 22.3 kDa
Gene Name DIRAS family GTPase 2
Database Link
Background DIRAS2 belongs to a distinct branch of the functionally diverse Ras (see HRAS; MIM 190020) superfamily of monomeric GTPases. supplied by OMIM, Apr 2004. ##Evidence-Data-START## Transcript exon combination :: AK122986.1, BC008065.2 ECO:0000332 RNAseq introns :: single sample supports all introns ERS025084, ERS025085 ECO:0000348 ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.
Synonyms Di-Ras2
Reference Data
Protein Categories Intracellular Proteins
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Other "OTI8A5" antibodies (4)
SKU Description Size Price
TA809398 DIRAS2 mouse monoclonal antibody,clone OTI8A5 100 ul
$447.00
TA809398AM DIRAS2 mouse monoclonal antibody,clone OTI8A5, Biotinylated 100 ul
$509.00
TA809398BM DIRAS2 mouse monoclonal antibody,clone OTI8A5, HRP conjugated 100 ul
$509.00
TA809398S DIRAS2 mouse monoclonal antibody,clone OTI8A5 30 ul
$200.00

file-alt Citations

The small GTP-binding Ras-like protein DIRAS2 promotes cell proliferation in oral leukoplakia via the RAF/MEK/MAPK pathway
Li, Tian, Li et al
Tissue Cell (2025) 96, 103037 DOI: 10.1016/j.tice.2025.103037
Cited by 4
AI Summary: OriGene's anti-DIRAS2 antibody was used in this study to detect DIRAS2 protein expression, contributing to the investigation of its role in promoting cell proliferation in oral leukoplakia via the RAF/MEK/MAPK pathway.
Snippet: Membranes were then blocked with 5 % skim milk and incubated overnight at 4 °C with antibodies against the target proteins as follows: anti-DIRAS2 (1:10000, Origene, China), anti-PCNA (1:1000, Proteintech, China), anti-p-MEK1/2 (1:1000, Proteintech, China), and anti-p-ERK (1:1000, CST, USA). …
WB
DIRAS2 Contributes to Radiation Resistance of Renal Cell Carcinoma Via Autophagy Induction and MKK4-JNK1 Pathway Activation
Cai, He, Yue et al
Research Square (2022)
Snippet: Subsequently, slices were incubated with a mouse polyclonal DIRAS2 antibody (Origene, TA809398), diluted in 1% goat serum (1:500) at 4 C overnight. After incubated with horseradish peroxidase (HRP)-conjugated secondary antibody for 1h at room temperature
IHC
RAS-related GTPases DIRAS1 and DIRAS2 induce autophagic cancer cell death and are required for autophagy in murine ovarian cancer cells
Sutton, Yang, Huang et al
Autophagy (2018)
AI Summary: In this study, OriGene products—including the anti-DIRAS2 antibody (TA809398) and pCMV-DIRAS1 and pCMV-DIRAS2 mouse and human plasmids (SC100097)—were used to detect DIRAS2 protein expression and to re-express DIRAS1 and DIRAS2 in cancer cells, enabling the investigation of their roles in autophagy and cancer cell death.
Snippet: other members of the DIRAS family. Antibody against DIRAS2 (TA 809398) was purchased from Origene. AKT (sc-514302) and MAPK/ERK (sc-514302) antibodies pCMV-DIRAS1 and pCMV- DIRAS2 mouse and human plasmids were purchased from Origene (SC100097
Showing 1-3 of 3 papers.
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