Transglutaminase 2 (TGM2) Mouse Monoclonal Antibody [Clone ID: OTI4H5]

SKU CF809245

Carrier-free (BSA/glycerol-free) TGM2 mouse monoclonal antibody,clone OTI4H5

Product Data

• Clone Name: OTI4H5
• Application: IHC, WB
• Recommended Dilution: WB 1:500, IHC 1:1000
• Reactivity: Human
• Antibody Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Full length human recombinant protein of human TGM2 (NP_004604) produced in HEK293T cell.
• Buffer: Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
• Reconstitution Method: For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Ambient
• Predicted Protein Size: 77.1 kDa
• Gene Name: transglutaminase 2
• Database Link:
  NP_004604
  P21980
• Background: Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. The protein encoded by this gene acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. Finally, the encoded protein is the autoantigen implicated in celiac disease. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
• Synonyms: G-ALPHA-h; GNAH; HEL-S-45; TG2; TGC

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Huntington's disease