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MAP3K8 Mouse Monoclonal Antibody [Clone ID: OTI3D9]

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SKU
CF808390
Carrier-free (BSA/glycerol-free) MAP3K8 mouse monoclonal antibody, clone OTI3D9 (formerly 3D9)
Size:
100 ug
Formulation:
Carrier-free Standard
Conjugation:
Unconjugated
  $620.00
3 Days*
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View other "MAP3K8 or NM_005204" antibodies

Specifications
Specifications
Product Data
Clone Name OTI3D9
Application WB
Recommended Dilution WB 1:500
Reactivity Human, Mouse, Rat
Antibody Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Human recombinant protein fragment corresponding to amino acids 277-461 of human MAP3K8(NP_005195) produced in E.coli.
Buffer Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Ambient
Predicted Protein Size 52.7 kDa
Gene Name mitogen-activated protein kinase kinase kinase 8
Database Link
Background This gene is an oncogene that encodes a member of the serine/threonine protein kinase family. The encoded protein localizes to the cytoplasm and can activate both the MAP kinase and JNK kinase pathways. This protein was shown to activate IkappaB kinases, and thus induce the nuclear production of NF-kappaB. This protein was also found to promote the production of TNF-alpha and IL-2 during T lymphocyte activation. This gene may also utilize a downstream in-frame translation start codon, and thus produce an isoform containing a shorter N-terminus. The shorter isoform has been shown to display weaker transforming activity. Alternate splicing results in multiple transcript variants that encode the same protein. provided by RefSeq, Sep 2011
Synonyms AURA2; c-COT; COT; EST; ESTF; MEKK8; Tpl-2; TPL2
Reference Data
Protein Categories Enzyme: Kinases, Intracellular Proteins
Protein Families Druggable Genome, Protein Kinase
Protein Pathways MAPK signaling pathway, T cell receptor signaling pathway, Toll-like receptor signaling pathway
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Other "OTI3D9" antibodies (4)
SKU Description Size Price
TA808390 MAP3K8 mouse monoclonal antibody, clone OTI3D9 (formerly 3D9) 100 ul
$447.00
TA808390AM MAP3K8 mouse monoclonal antibody, clone OTI3D9 (formerly 3D9), Biotinylated 100 ul
$509.00
TA808390BM MAP3K8 mouse monoclonal antibody, clone OTI3D9 (formerly 3D9), HRP conjugated 100 ul
$509.00
TA808390S MAP3K8 mouse monoclonal antibody, clone OTI3D9 (formerly 3D9) 30 ul
$200.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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