PCDHGC5 Mouse Monoclonal Antibody [Clone ID: OTI2E1]
Specifications
| Product Data | |
| Clone Name | OTI2E1 |
|---|---|
| Application | IHC, WB |
| Recommended Dilution | WB 1:2000, IHC 1:150 |
| Reactivity | Human, Mouse, Rat |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 35-258 of human PCDHGC5(NP_115783) produced in E.coli. |
| Buffer | Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose) |
| Reconstitution Method | For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific) |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Ambient |
| Gene Name | protocadherin gamma subfamily C, 5 |
| Database Link | |
| Background | This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes. [provided by RefSeq, Jul |
| Synonyms | PCDH-GAMMA-C5 |
| Reference Data | |
| Protein Categories | Membrane Proteins |
| Protein Families | Transmembrane |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other "OTI2E1" antibodies (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| TA807819 | PCDHGC5 mouse monoclonal antibody, clone OTI2E1 (formerly 2E1) | 100 ul |
$447.00
|
|
| TA807819AM | PCDHGC5 mouse monoclonal antibody, clone OTI2E1 (formerly 2E1), Biotinylated | 100 ul |
$509.00
|
|
| TA807819BM | PCDHGC5 mouse monoclonal antibody, clone OTI2E1 (formerly 2E1), HRP conjugated | 100 ul |
$509.00
|
|
| TA807819S | PCDHGC5 mouse monoclonal antibody, clone OTI2E1 (formerly 2E1) | 30 ul |
$200.00
|
|
Citations
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