ATF1 Mouse Monoclonal Antibody [Clone ID: OTI2B4]
SKU
CF807630
Carrier-free (BSA/glycerol-free) ATF1 mouse monoclonal antibody, clone OTI2B4 (formerly 2B4)
$620.00
3 Days*
Specifications
| Product Data | |
| Clone Name | OTI2B4 |
|---|---|
| Application | IHC, WB |
| Recommended Dilution | WB 1:2000, IHC 1:150 |
| Reactivity | Human, Mouse, Rat |
| Antibody Host | Mouse |
| Isotype | IgG2b |
| Clonality | Monoclonal |
| Immunogen | Full length human recombinant protein of human ATF1(NP_005162) produced in E.coli. |
| Buffer | Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose) |
| Reconstitution Method | For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific) |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Ambient |
| Predicted Protein Size | 29.1 kDa |
| Gene Name | activating transcription factor 1 |
| Database Link | |
| Background | This gene encodes an activating transcription factor, which belongs to the ATF subfamily and bZIP (basic-region leucine zipper) family. It influences cellular physiologic processes by regulating the expression of downstream target genes, which are related to growth, survival, and other cellular activities. This protein is phosphorylated at serine 63 in its kinase-inducible domain by serine/threonine kinases, cAMP-dependent protein kinase A, calmodulin-dependent protein kinase I/II, mitogen- and stress-activated protein kinase and cyclin-dependent kinase 3 (cdk-3). Its phosphorylation enhances its transactivation and transcriptional activities, and enhances cell transformation. Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in angiomatoid fibrous histiocytoma and clear cell sarcoma. This gene has a pseudogene on chromosome 6. provided by RefSeq, Aug 2010 |
| Synonyms | EWS-ATF1; FUS/ATF-1; TREB36 |
| Reference Data | |
| Protein Categories | Cancer: Sarcoma, Growth Factors, Intracellular Proteins, Transciption Factors |
| Protein Families | Druggable Genome, Transcription Factors |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other "OTI2B4" antibodies (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| TA807630 | ATF1 mouse monoclonal antibody, clone OTI2B4 (formerly 2B4) | 100 ul |
$447.00
|
|
| TA807630AM | ATF1 mouse monoclonal antibody, clone OTI2B4 (formerly 2B4), Biotinylated | 100 ul |
$509.00
|
|
| TA807630BM | ATF1 mouse monoclonal antibody, clone OTI2B4 (formerly 2B4), HRP conjugated | 100 ul |
$509.00
|
|
| TA807630S | ATF1 mouse monoclonal antibody, clone OTI2B4 (formerly 2B4) | 30 ul |
$200.00
|
|
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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