FBXO8 Mouse Monoclonal Antibody [Clone ID: OTI7E12]
Specifications
| Product Data | |
| Clone Name | OTI7E12 |
|---|---|
| Application | WB |
| Recommended Dilution | WB 1:2000 |
| Reactivity | Human, Mouse, Rat |
| Antibody Host | Mouse |
| Isotype | IgG2a |
| Clonality | Monoclonal |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1-231 of human FBXO8(NP_036312) produced in E.coli. |
| Buffer | Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose) |
| Reconstitution Method | For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific) |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Ambient |
| Predicted Protein Size | 36.9 kDa |
| Gene Name | F-box protein 8 |
| Database Link | |
| Background | This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. It contains a C-terminal amino acid sequence that bears a significant similarity with a portion of yeast Sec7p, a critical regulator of vesicular protein transport. This human protein may interact with ADP-ribosylation factor(s)(ARFs) and exhibit ARF-GEF (guanine nucleotide exchange factor) activity. provided by RefSeq, Jul 2008 |
| Synonyms | DC10; FBS; FBX8 |
| Reference Data | |
| Protein Categories | Intracellular Proteins |
| Protein Families | Druggable Genome |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other "OTI7E12" antibodies (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| TA807552 | FBXO8 mouse monoclonal antibody, clone OTI7E12 (formerly 7E12) | 100 ul |
$447.00
|
|
| TA807552AM | FBXO8 mouse monoclonal antibody, clone OTI7E12 (formerly 7E12), Biotinylated | 100 ul |
$509.00
|
|
| TA807552BM | FBXO8 mouse monoclonal antibody, clone OTI7E12 (formerly 7E12), HRP conjugated | 100 ul |
$509.00
|
|
| TA807552S | FBXO8 mouse monoclonal antibody, clone OTI7E12 (formerly 7E12) | 30 ul |
$200.00
|
|
Citations
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