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PAK4 Mouse Monoclonal Antibody [Clone ID: OTI3C3]

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SKU
CF807368
Carrier-free (BSA/glycerol-free) PAK4 mouse monoclonal antibody, clone OTI3C3 (formerly 3C3)
Size:
100 ug
Formulation:
Carrier-free Standard
Conjugation:
Unconjugated
  $620.00
4 Weeks*
Bulk/Customize

View other "PAK4 or NM_005884" antibodies

Specifications
Specifications
Product Data
Clone Name OTI3C3
Application WB
Recommended Dilution WB 1:2000
Reactivity Human, Mouse, Rat
Antibody Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Human recombinant protein fragment corresponding to amino acids 1-308 of human PAK4(NP_005875) produced in E.coli.
Buffer Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Ambient
Predicted Protein Size 63.9 kDa
Gene Name p21 (RAC1) activated kinase 4
Database Link
Background PAK proteins, a family of serine/threonine p21-activating kinases, include PAK1, PAK2, PAK3 and PAK4. PAK proteins are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. They serve as targets for the small GTP binding proteins Cdc42 and Rac and have been implicated in a wide range of biological activities. PAK4 interacts specifically with the GTP-bound form of Cdc42Hs and weakly activates the JNK family of MAP kinases. PAK4 is a mediator of filopodia formation and may play a role in the reorganization of the actin cytoskeleton. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. provided by RefSeq, Jul 2008
Synonyms effector for Cdc42Hs; p21 protein (Cdc42; p21(CDKN1A)-activated kinase 4; p21-activated kinase 4; protein kinase related to S. cerevisiae STE20; Rac)-activated kinase 4
Reference Data
Protein Categories Enzyme: Kinases, Intracellular Proteins
Protein Families Druggable Genome, Protein Kinase
Protein Pathways Axon guidance, ErbB signaling pathway, Focal adhesion, Regulation of actin cytoskeleton, Renal cell carcinoma, T cell receptor signaling pathway
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Other "OTI3C3" antibodies (4)
SKU Description Size Price
TA807368 PAK4 mouse monoclonal antibody, clone OTI3C3 (formerly 3C3) 100 ul
$447.00
TA807368AM PAK4 mouse monoclonal antibody, clone OTI3C3 (formerly 3C3), Biotinylated 100 ul
$509.00
TA807368BM PAK4 mouse monoclonal antibody, clone OTI3C3 (formerly 3C3), HRP conjugated 100 ul
$509.00
TA807368S PAK4 mouse monoclonal antibody, clone OTI3C3 (formerly 3C3) 30 ul
$200.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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