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NR2C2 Mouse Monoclonal Antibody [Clone ID: OTI4B1]

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SKU
CF807275
Carrier-free (BSA/glycerol-free) NR2C2 mouse monoclonal antibody, clone OTI4B1 (formerly 4B1)
Size:
100 ug
Formulation:
Carrier-free Standard
Conjugation:
Unconjugated
  $620.00
3 Days*
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View other "NR2C2 or NM_003298" antibodies

Specifications
Specifications
Product Data
Clone Name OTI4B1
Application IHC, WB
Recommended Dilution WB 1:2000, IHC 1:150
Reactivity Human, Mouse, Rat
Antibody Host Mouse
Isotype IgG2b
Clonality Monoclonal
Immunogen Human recombinant protein fragment corresponding to amino acids 1-241 of human NR2C2(NP_003289) produced in E.coli.
Buffer Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Ambient
Predicted Protein Size 67.2 kDa
Gene Name nuclear receptor subfamily 2 group C member 2
Database Link
Background This gene encodes a protein that belongs to the nuclear hormone receptor family. Members of this family act as ligand-activated transcription factors and function in many biological processes such as development, cellular differentiation and homeostasis. The activated receptor/ligand complex is translocated to the nucleus where it binds to hormone response elements of target genes. The protein encoded by this gene plays a role in protecting cells from oxidative stress and damage induced by ionizing radiation. The lack of a similar gene in mouse results in growth retardation, severe spinal curvature, subfertility, premature aging, and prostatic intraepithelial neoplasia (PIN) development. Alternative splicing results in multiple transcript variants encoding different isoforms. provided by RefSeq, Apr 2014
Synonyms TAK1; TR4
Reference Data
Protein Categories Growth Factors, Intracellular Proteins, Transciption Factors
Protein Families Druggable Genome, Nuclear Hormone Receptor, Transcription Factors
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Other "OTI4B1" antibodies (4)
SKU Description Size Price
TA807275 NR2C2 mouse monoclonal antibody, clone OTI4B1 (formerly 4B1) 100 ul
$447.00
TA807275AM NR2C2 mouse monoclonal antibody, clone OTI4B1 (formerly 4B1), Biotinylated 100 ul
$509.00
TA807275BM NR2C2 mouse monoclonal antibody, clone OTI4B1 (formerly 4B1), HRP conjugated 100 ul
$509.00
TA807275S NR2C2 mouse monoclonal antibody, clone OTI4B1 (formerly 4B1) 30 ul
$200.00

file-alt Citations

Human microglia maturation is underpinned by specific gene regulatory networks
Han, Li, Hansen et al
Immunity (2023) 56 (9), 2152-2171.e13 DOI: 10.1016/j.immuni.2023.07.016
Cited by 73
AI Summary: In this study, the OriGene Mouse anti-NR2C2 (OTI4B1) antibody (TA807275) was used to investigate the expression of NR2C2 as part of the analysis of gene regulatory networks underlying human microglia maturation.
Snippet: … Save;Rabbit anti-PU.1 (9G7) Cell Signaling 2258;RRID: AB_2186909 Mouse anti-NR2C2 (OTI4B1) Origene TA807275, RRID:none Rabbit anti-IRF7 (G-8) Santa Cruz Antibodies sc-74472;RRID:AB_2280489 Mouse anti-MiTF Active Motif 91201;RRID: AB_2793801 Rabbit anti-PRDM1 Rockland 600-401-B52;RRID:AB_1961755
Showing 1-1 of 1 papers.
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