C2 Mouse Monoclonal Antibody [Clone ID: OTI1A7]
$620.00
3 Days*
Specifications
| Product Data | |
| Clone Name | OTI1A7 |
|---|---|
| Application | IHC, WB |
| Recommended Dilution | WB 1:500, IHC 1:150 |
| Reactivity | Human |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 469-752 of human C2(NP_000054) produced in E.coli. |
| Buffer | Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose) |
| Reconstitution Method | For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific) |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Ambient |
| Predicted Protein Size | 81 kDa |
| Gene Name | complement C2 |
| Database Link | |
| Background | Component C2 is a serum glycoprotein that functions as part of the classical pathway of the complement system. Activated C1 cleaves C2 into C2a and C2b. The serine proteinase C2a then combines with complement factor 4b to create the C3 or C5 convertase. Deficiency of C2 has been reported to associated with certain autoimmune diseases and SNPs in this gene have been associated with altered susceptibility to age-related macular degeneration. This gene localizes within the class III region of the MHC on the short arm of chromosome 6. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described in publications but their full-length sequence has not been determined. provided by RefSeq, Mar 2009 |
| Synonyms | ARMD14; CO2 |
| Reference Data | |
| Protein Categories | Allergies and autoimmune diseases, Enzyme: Peptidases, Intracellular Proteins, Nervous system Diseases, Secreated Proteins |
| Protein Families | Druggable Genome, Protease, Secreted Protein |
| Protein Pathways | Complement and coagulation cascades, Systemic lupus erythematosus |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other "OTI1A7" antibodies (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| TA807163 | C2 mouse monoclonal antibody,clone OTI1A7 | 100 ul |
$447.00
|
|
| TA807163AM | C2 mouse monoclonal antibody,clone OTI1A7, Biotinylated | 100 ul |
$509.00
|
|
| TA807163BM | C2 mouse monoclonal antibody,clone OTI1A7, HRP conjugated | 100 ul |
$509.00
|
|
| TA807163S | C2 mouse monoclonal antibody,clone OTI1A7 | 30 ul |
$200.00
|
|
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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