UBE2D2 Mouse Monoclonal Antibody [Clone ID: OTI1D11]

SKU
CF806601
Carrier-free (BSA/glycerol-free) UBE2D2 mouse monoclonal antibody, clone OTI1D11 (formerly 1D11)
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    Antibodies made against full-length proteins as antigens.

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$600.00
3 Days*
Specifications
Product Data
Clone Name OTI1D11
Application IHC, WB
Recommended Dilution WB 1:2000, IHC 1:150
Reactivity Human, Mouse, Rat
Antibody Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Full length human recombinant protein of human UBE2D2 (NP_003330) produced in E.coli.
Buffer Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Ambient
Predicted Protein Size 16.6 kDa
Gene Name ubiquitin conjugating enzyme E2 D2
Database Link
Background Regulated degradation of misfolded, damaged or short-lived proteins in eukaryotes occurs via the ubiquitin (Ub)-proteasome system (UPS). An integral part of the UPS system is the ubiquitination of target proteins and covalent linkage of Ub-containing proteins to form polymeric chains, marking them as targets for 26S proteasome-mediated degradation. Ubiquitination of proteins is mediated by a cascade of enzymes which includes E1 (ubiquitin activating), E2 (ubiquitin conjugating), and E3 (ubiquitin ligases) enzymes. This gene encodes a member of the E2 enzyme family. Substrates of this enzyme include the tumor suppressor protein p53 and peroxisomal biogenesis factor 5 (PEX5). Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, May 2013]
Synonyms E2(17)KB2; PUBC1; UBC4; UBC4/5; UBCH4; UBCH5B
Reference Data
Protein Pathways Ubiquitin mediated proteolysis
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SKU Description Size Price
TA806601 UBE2D2 mouse monoclonal antibody, clone OTI1D11 (formerly 1D11) 100 ul
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TA806601BM UBE2D2 mouse monoclonal antibody, clone OTI1D11 (formerly 1D11), HRP conjugated 100 ul
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TA806601S UBE2D2 mouse monoclonal antibody, clone OTI1D11 (formerly 1D11) 30 ul
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Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.