Lipin 1 (LPIN1) Mouse Monoclonal Antibody [Clone ID: OTI2C8]
Specifications
| Product Data | |
| Clone Name | OTI2C8 |
|---|---|
| Application | WB |
| Recommended Dilution | WB 1:2000 |
| Reactivity | Human, Mouse, Rat |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1-274 of human LPIN1(NP_663731) produced in E.coli. |
| Buffer | Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose) |
| Reconstitution Method | For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific) |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Ambient |
| Predicted Protein Size | 98.5 kDa |
| Gene Name | lipin 1 |
| Database Link | |
| Background | This gene encodes a magnesium-ion-dependent phosphatidic acid phosphohydrolase enzyme that catalyzes the penultimate step in triglyceride synthesis including the dephosphorylation of phosphatidic acid to yield diacylglycerol. Expression of this gene is required for adipocyte differentiation and it also functions as a nuclear transcriptional coactivator with some peroxisome proliferator-activated receptors to modulate expression of other genes involved in lipid metabolism. Mutations in this gene are associated with metabolic syndrome, type 2 diabetes, and autosomal recessive acute recurrent myoglobinuria (ARARM). This gene is also a candidate for several human lipodystrophy syndromes. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their full-length structures have not been determined. provided by RefSeq, May 2012 |
| Synonyms | PAP1 |
| Reference Data | |
| Protein Categories | Intracellular Proteins |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other "OTI2C8" antibodies (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| TA806239 | LPIN1 mouse monoclonal antibody, clone OTI2C8 (formerly 2C8) | 100 ul |
$447.00
|
|
| TA806239AM | LPIN1 mouse monoclonal antibody, clone OTI2C8 (formerly 2C8), Biotinylated | 100 ul |
$509.00
|
|
| TA806239BM | LPIN1 mouse monoclonal antibody, clone OTI2C8 (formerly 2C8), HRP conjugated | 100 ul |
$509.00
|
|
| TA806239S | LPIN1 mouse monoclonal antibody, clone OTI2C8 (formerly 2C8) | 30 ul |
$200.00
|
|
Citations
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