MMP7 Mouse Monoclonal Antibody [Clone ID: OTI2E1]
Specifications
| Product Data | |
| Clone Name | OTI2E1 |
|---|---|
| Application | WB |
| Recommended Dilution | WB 1:2000 |
| Reactivity | Human |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 95-267 of human MMP7 (NP_002414) produced in E.coli. |
| Buffer | Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose) |
| Reconstitution Method | For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific) |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Ambient |
| Predicted Protein Size | 19.1 kDa |
| Gene Name | matrix metallopeptidase 7 |
| Database Link | |
| Background | Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades proteoglycans, fibronectin, elastin and casein and differs from most MMP family members in that it lacks a conserved C-terminal protein domain. The enzyme is involved in wound healing, and studies in mice suggest that it regulates the activity of defensins in intestinal mucosa. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. provided by RefSeq, Jul 2008 |
| Synonyms | MMP-7; MPSL1; PUMP-1 |
| Reference Data | |
| Protein Categories | Enzyme: Peptidases, Secreated Proteins |
| Protein Families | Druggable Genome, Protease |
| Protein Pathways | Wnt signaling pathway |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other "OTI2E1" antibodies (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| TA804871 | MMP7 mouse monoclonal antibody, clone OTI2E1 (formerly 2E1) | 100 ul |
$447.00
|
|
| TA804871AM | MMP7 mouse monoclonal antibody, clone OTI2E1 (formerly 2E1), Biotinylated | 100 ul |
$509.00
|
|
| TA804871BM | MMP7 mouse monoclonal antibody, clone OTI2E1 (formerly 2E1), HRP conjugated | 100 ul |
$509.00
|
|
| TA804871S | MMP7 mouse monoclonal antibody, clone OTI2E1 (formerly 2E1) | 30 ul |
$200.00
|
|
Citations
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