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DCC Mouse Monoclonal Antibody [Clone ID: OTI5D10]

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SKU
CF804517
Carrier-free (glycerol/BSA-free) DCC mouse monoclonal antibody, clone OTI5D10 (formerly 5D10)
Size:
100 ug
Formulation:
Carrier-free Standard
Conjugation:
Unconjugated
  $620.00
3 Days*
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View other "DCC or NM_005215" antibodies

Specifications
Specifications
Product Data
Clone Name OTI5D10
Application WB
Recommended Dilution WB 1:2000
Reactivity Human, Mouse, Rat
Antibody Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Full length human recombinant protein of human DCC (NP_005206) produced in HEK293T cell.
Buffer Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Ambient
Predicted Protein Size 158.3 kDa
Gene Name DCC netrin 1 receptor
Database Link
Background This gene encodes a netrin 1 receptor. The transmembrane protein is a member of the immunoglobulin superfamily of cell adhesion molecules, and mediates axon guidance of neuronal growth cones towards sources of netrin 1 ligand. The cytoplasmic tail interacts with the tyrosine kinases Src and focal adhesion kinase (FAK, also known as PTK2) to mediate axon attraction. The protein partially localizes to lipid rafts, and induces apoptosis in the absence of ligand. The protein functions as a tumor suppressor, and is frequently mutated or downregulated in colorectal cancer and esophageal carcinoma. provided by RefSeq, Oct 2009
Synonyms CRC18; CRCR1; IGDCC1; MRMV1; NTN1R1
Reference Data
Protein Categories Cancer: Gastrointestinal, Intracellular Proteins, Membrane Proteins, Nervous system Diseases
Protein Families Druggable Genome, Transmembrane
Protein Pathways Axon guidance, Colorectal cancer, Pathways in cancer
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Other "OTI5D10" antibodies (4)
SKU Description Size Price
TA804517 DCC mouse monoclonal antibody, clone OTI5D10 (formerly 5D10) 100 ul
$447.00
TA804517AM DCC mouse monoclonal antibody, clone OTI5D10 (formerly 5D10), Biotinylated 100 ul
$509.00
TA804517BM DCC mouse monoclonal antibody, clone OTI5D10 (formerly 5D10), HRP conjugated 100 ul
$509.00
TA804517S DCC mouse monoclonal antibody, clone OTI5D10 (formerly 5D10) 30 ul
$200.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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