ACE2 Mouse Monoclonal Antibody [Clone ID: OTI4D2] (Angiotensin Converting Enzyme 2)
Specifications
| Product Data | |
| Clone Name | OTI4D2 |
|---|---|
| Application | IHC, WB |
| Recommended Dilution | WB 1:200, IHC 1:150 |
| Reactivity | Human, Mouse, Rat |
| Antibody Host | Mouse |
| Isotype | IgG2a |
| Clonality | Monoclonal |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 18-237 of human ACE2 (NP_068576) produced in E.coli. |
| Buffer | Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose) |
| Reconstitution Method | For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific) |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Ambient |
| Gene Name | angiotensin converting enzyme 2 |
| Database Link | |
| Background | The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. The organ- and cell-specific expression of this gene suggests that it may play a role in the regulation of cardiovascular and renal function, as well as fertility. In addition, the encoded protein is a functional receptor for the spike glycoprotein of the human coronaviruses SARS and HCoV-NL63. provided by RefSeq, Jul 2008 |
| Synonyms | ACEH |
| Reference Data | |
| Protein Categories | Cytokines, Enzyme: Peptidases, Membrane Proteins, Secreated Proteins |
| Protein Families | Druggable Genome, Secreted Protein, Transmembrane |
| Protein Pathways | Renin-angiotensin system |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other "OTI4D2" antibodies (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| TA803841 | ACE2 mouse monoclonal antibody, clone OTI4D2 (formerly 4D2) | 100 ul |
$447.00
|
|
| TA803841AM | ACE2 mouse monoclonal antibody, clone OTI4D2 (formerly 4D2), Biotinylated | 100 ul |
$509.00
|
|
| TA803841BM | ACE2 mouse monoclonal antibody, clone OTI4D2 (formerly 4D2), HRP conjugated | 100 ul |
$509.00
|
|
| TA803841S | ACE2 mouse monoclonal antibody, clone OTI4D2 (formerly 4D2) | 30 ul |
$200.00
|
|
Citations
Luo, DU
Zhongguo Dang Dai Er Ke Za Zhi (2020) 22 (9), 1043-1046
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