UBE2D1 Mouse Monoclonal Antibody [Clone ID: OTI1E7]
Specifications
| Product Data | |
| Clone Name | OTI1E7 |
|---|---|
| Application | WB |
| Recommended Dilution | WB 1:2000 |
| Reactivity | Human, Mouse, Rat |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Full length human recombinant protein of human UBE2D1 (NP_003329) produced in E.coli. |
| Buffer | Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose) |
| Reconstitution Method | For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific) |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Ambient |
| Gene Name | ubiquitin conjugating enzyme E2 D1 |
| Database Link | |
| Background | The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is closely related to a stimulator of iron transport (SFT), and is up-regulated in hereditary hemochromatosis. It also functions in the ubiquitination of the tumor-suppressor protein p53 and the hypoxia-inducible transcription factor HIF1alpha by interacting with the E1 ubiquitin-activating enzyme and the E3 ubiquitin-protein ligases. Two transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Mar 2011 |
| Synonyms | E2(17)KB1; SFT; UBC4/5; UBCH5; UBCH5A |
| Reference Data | |
| Protein Categories | Intracellular Proteins |
| Protein Pathways | Ubiquitin mediated proteolysis |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other "OTI1E7" antibodies (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| TA803633 | UBE2D1 mouse monoclonal antibody, clone OTI1E7 (formerly 1E7) | 100 ul |
$447.00
|
|
| TA803633AM | UBE2D1 mouse monoclonal antibody, clone OTI1E7 (formerly 1E7), Biotinylated | 100 ul |
$509.00
|
|
| TA803633BM | UBE2D1 mouse monoclonal antibody, clone OTI1E7 (formerly 1E7), HRP conjugated | 100 ul |
$509.00
|
|
| TA803633S | UBE2D1 mouse monoclonal antibody, clone OTI1E7 (formerly 1E7) | 30 ul |
$200.00
|
|
Citations
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