GBA Mouse Monoclonal Antibody [Clone ID: OTI2B2]

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SKU
CF803376
Carrier-free (BSA/glycerol-free) GBA mouse monoclonal antibody, clone OTI2B2 (formerly 2B2)
  $620.00
3 Days*
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Specifications
Specifications
Product Data
Clone Name OTI2B2
Application IHC, WB
Recommended Dilution WB 1:2000
Reactivity Human, Mouse, Rat
Antibody Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Human recombinant protein fragment corresponding to amino acids 40-315 of human GBA (NP_000148) produced in E.coli.
Buffer Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Ambient
Predicted Protein Size 55.5 kDa
Gene Name glucosylceramidase beta
Database Link
Background This gene encodes a lysosomal membrane protein that cleaves the beta-glucosidic linkage of glycosylceramide, an intermediate in glycolipid metabolism. Mutations in this gene cause Gaucher disease, a lysosomal storage disease characterized by an accumulation of glucocerebrosides. A related pseudogene is approximately 12 kb downstream of this gene on chromosome 1. Alternative splicing results in multiple transcript variants. provided by RefSeq, Jan 2010
Synonyms GBA1; GCB; GLUC
Reference Data
Protein Categories Intracellular Proteins, Nervous system: Neurodegenerative diseases
Protein Families Druggable Genome
Protein Pathways Lysosome, Metabolic pathways, Other glycan degradation, Sphingolipid metabolism
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Other "OTI2B2" antibodies (4)
SKU Description Size Price
TA803376 GBA mouse monoclonal antibody, clone OTI2B2 (formerly 2B2) 100 ul
$447.00
TA803376AM GBA mouse monoclonal antibody,clone 2B2, Biotinylated 100 ul
$509.00
TA803376BM GBA mouse monoclonal antibody,clone 2B2, HRP conjugated 100 ul
$509.00
TA803376S GBA mouse monoclonal antibody, clone OTI2B2 (formerly 2B2) 30 ul
$200.00

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