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RASGRP3 Mouse Monoclonal Antibody [Clone ID: OTI5D2]

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SKU
CF801532
Carrier-free (BSA/glycerol-free) RASGRP3 mouse monoclonal antibody, clone OTI5D2 (formerly 5D2)
Size:
100 ug
Formulation:
Carrier-free Standard
Conjugation:
Unconjugated
  $620.00
3 Days*
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View other "RASGRP3 or NM_170672" antibodies

Specifications
Specifications
Product Data
Clone Name OTI5D2
Application WB
Recommended Dilution WB 1:2000
Reactivity Human
Antibody Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Human recombinant protein fragment corresponding to amino acids 380-690 of human RASGRP3 (NP_733772) produced in E.coli.
Buffer Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Ambient
Predicted Protein Size 78.2 kDa
Gene Name RAS guanyl releasing protein 3
Database Link
Background Members of the RAS (see HRAS; MIM 190020) subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP- and active GTP-bound states. Guanine nucleotide exchange factors (GEFs), such as RASGRP3, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP-bound state and are the key link between cell surface receptors and RAS activation (Rebhun et al., 2000 PubMed 10934204). supplied by OMIM, Mar 2008
Synonyms GRP3
Note WB application:Only overexpression results are guaranteed, not endogenous
Reference Data
Protein Categories Intracellular Proteins
Protein Pathways B cell receptor signaling pathway, MAPK signaling pathway
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Other "OTI5D2" antibodies (4)
SKU Description Size Price
TA801532 RASGRP3 mouse monoclonal antibody, clone OTI5D2 (formerly 5D2) 100 ul
$447.00
TA801532AM RASGRP3 mouse monoclonal antibody,clone 5D2, Biotinylated 100 ul
$509.00
TA801532BM RASGRP3 mouse monoclonal antibody,clone 5D2, HRP conjugated 100 ul
$509.00
TA801532S RASGRP3 mouse monoclonal antibody, clone OTI5D2 (formerly 5D2) 30 ul
$200.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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