RASGRP3 Mouse Monoclonal Antibody [Clone ID: OTI2G7]
Specifications
| Product Data | |
| Clone Name | OTI2G7 |
|---|---|
| Application | IHC |
| Recommended Dilution | IHC 1:150 |
| Reactivity | Human, Mouse, Rat |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 380-690 of human RASGRP3 (NP_733772) produced in E.coli. |
| Buffer | Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose) |
| Reconstitution Method | For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific) |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Ambient |
| Predicted Protein Size | 78.2 kDa |
| Gene Name | RAS guanyl releasing protein 3 |
| Database Link | |
| Background | Members of the RAS (see HRAS; MIM 190020) subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP- and active GTP-bound states. Guanine nucleotide exchange factors (GEFs), such as RASGRP3, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP-bound state and are the key link between cell surface receptors and RAS activation (Rebhun et al., 2000 PubMed 10934204). supplied by OMIM, Mar 2008 |
| Synonyms | GRP3 |
| Reference Data | |
| Protein Categories | Intracellular Proteins |
| Protein Pathways | B cell receptor signaling pathway, MAPK signaling pathway |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other "OTI2G7" antibodies (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| TA801465 | RASGRP3 mouse monoclonal antibody,clone OTI2G7 | 100 ul |
$447.00
|
|
| TA801465AM | RASGRP3 mouse monoclonal antibody,clone 2G7, Biotinylated | 100 ul |
$509.00
|
|
| TA801465BM | RASGRP3 mouse monoclonal antibody,clone 2G7, HRP conjugated | 100 ul |
$509.00
|
|
| TA801465S | RASGRP3 mouse monoclonal antibody,clone OTI2G7 | 30 ul |
$200.00
|
|
Citations
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