Tyrosinase (TYR) Mouse Monoclonal Antibody [Clone ID: OTI1F3]
Specifications
| Product Data | |
| Clone Name | OTI1F3 |
|---|---|
| Application | IHC |
| Recommended Dilution | IHC 1:150 |
| Reactivity | Human, Mouse, Rat |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 19-320 of human TYR (NP_000363) produced in E.coli. |
| Buffer | Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose) |
| Reconstitution Method | For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific) |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Ambient |
| Predicted Protein Size | 58.3 kDa |
| Gene Name | tyrosinase |
| Database Link | |
| Background | The enzyme encoded by this gene catalyzes the first 2 steps, and at least 1 subsequent step, in the conversion of tyrosine to melanin. The enzyme has both tyrosine hydroxylase and dopa oxidase catalytic activities, and requires copper for function. Mutations in this gene result in oculocutaneous albinism, and nonpathologic polymorphisms result in skin pigmentation variation. The human genome contains a pseudogene similar to the 3' half of this gene. provided by RefSeq, Oct 2008 |
| Synonyms | ATN; CMM8; OCA1; OCA1A; OCAIA; SHEP3 |
| Reference Data | |
| Protein Categories | Membrane Proteins |
| Protein Families | Transmembrane |
| Protein Pathways | Melanogenesis, Metabolic pathways, Riboflavin metabolism, Tyrosine metabolism |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other "OTI1F3" antibodies (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| TA801362 | TYR mouse monoclonal antibody, clone OTI1F3 (formerly 1F3) | 100 ul |
$447.00
|
|
| TA801362AM | TYR mouse monoclonal antibody,clone 1F3, Biotinylated | 100 ul |
$509.00
|
|
| TA801362BM | TYR mouse monoclonal antibody,clone 1F3, HRP conjugated | 100 ul |
$509.00
|
|
| TA801362S | TYR mouse monoclonal antibody, clone OTI1F3 (formerly 1F3) | 30 ul |
$200.00
|
|
Citations
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