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SF3A1 Mouse Monoclonal Antibody [Clone ID: OTI4D8]

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SKU
CF800588
Carrier-free (BSA/glycerol-free) SF3A1 mouse monoclonal antibody, clone OTI4D8 (formerly 4D8)
Size:
100 ug
Formulation:
Carrier-free Standard
Conjugation:
Unconjugated
  $620.00
3 Days*
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View other "SF3A1 or NM_005877" antibodies

Specifications
Specifications
Product Data
Clone Name OTI4D8
Application IHC
Recommended Dilution IHC 1:500
Reactivity Human, Mouse, Rat
Antibody Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Human recombinant protein fragment corresponding to amino acids 249-568 of human SF3A1 (NP_005868) produced in E.coli.
Buffer Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Ambient
Predicted Protein Size 88.7 kDa
Gene Name splicing factor 3a subunit 1
Database Link
Background This gene encodes subunit 1 of the splicing factor 3a protein complex. The splicing factor 3a heterotrimer includes subunits 1, 2 and 3 and is necessary for the in vitro conversion of 15S U2 snRNP into an active 17S particle that performs pre-mRNA splicing. Subunit 1 belongs to the SURP protein family; named for the SURP (also called SWAP or Suppressor-of-White-APricot) motifs that are thought to mediate RNA binding. Subunit 1 has tandemly repeated SURP motifs in its amino-terminal half while its carboxy-terminal half contains a proline-rich region and a ubiquitin-like domain. Binding studies with truncated subunit 1 derivatives demonstrated that the two SURP motifs are necessary for binding to subunit 3 while contacts with subunit 2 may occur through sequences carboxy-terminal to the SURP motifs. Alternative splicing results in multiple transcript variants encoding different isoforms. provided by RefSeq, Jul 2008
Synonyms PRP21; PRPF21; SAP114; SF3A120
Reference Data
Protein Categories Intracellular Proteins
Protein Families Druggable Genome
Protein Pathways Spliceosome
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Other "OTI4D8" antibodies (4)
SKU Description Size Price
TA800588 SF3A1 mouse monoclonal antibody, clone OTI4D8 (formerly 4D8) 100 ul
$447.00
TA800588AM SF3A1 mouse monoclonal antibody,clone 4D8, Biotinylated 100 ul
$509.00
TA800588BM SF3A1 mouse monoclonal antibody,clone 4D8, HRP conjugated 100 ul
$509.00
TA800588S SF3A1 mouse monoclonal antibody, clone OTI4D8 (formerly 4D8) 30 ul
$200.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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