CD4 Mouse Monoclonal Antibody [Clone ID: OTI5D9]

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SKU
CF800512
Carrier-free (BSA/glycerol-free) CD4 mouse monoclonal antibody, clone OTI5D9 (formerly 5D9)
  $620.00
3 Days*
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Specifications
Specifications
Product Data
Clone Name OTI5D9
Application IHC, WB
Recommended Dilution WB 1:2000, IHC 1:150
Reactivity Human
Antibody Host Mouse
Isotype IgG2a
Clonality Monoclonal
Immunogen Full length human recombinant protein of human CD4 (NP_000607) produced in HEK293T cell.
Buffer Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Ambient
Predicted Protein Size 48.3 kDa
Gene Name CD4 molecule
Database Link
Background This gene encodes a membrane glycoprotein of T lymphocytes that interacts with major histocompatibility complex class II antigenes and is also a receptor for the human immunodeficiency virus. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, and granulocytes. It is also expressed in specific regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene. provided by RefSeq, Aug 2010
Synonyms CD4mut; IMD79; OKT4D
Reference Data
Protein Categories ADC Targets, CD Markers, Immune system diseases, Intracellular Proteins, Membrane Proteins
Protein Families Adult stem cells, Druggable Genome, ES Cell Differentiation/IPS, Induced pluripotent stem cells, Transmembrane
Protein Pathways Antigen processing and presentation, Cell adhesion molecules (CAMs), Hematopoietic cell lineage, Primary immunodeficiency, T cell receptor signaling pathway
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Other "OTI5D9" antibodies (6)
SKU Description Size Price
TA600281 CD4 mouse monoclonal capture antibody, validated for Luminex assays 100 ug
$458.00
TA700300 CD4 biotinylated mouse monoclonal detection antibody, validated for Luminex assays 50 ug
$494.00
TA800512 CD4 mouse monoclonal antibody, clone OTI5D9 (formerly 5D9) 100 ul
$447.00
TA800512AM CD4 mouse monoclonal antibody,clone 5D9, Biotinylated 100 ul
$509.00
TA800512BM CD4 mouse monoclonal antibody,clone 5D9, HRP conjugated 100 ul
$509.00
TA800512S CD4 mouse monoclonal antibody, clone OTI5D9 (formerly 5D9) 30 ul
$200.00

file-alt Citations

Chronically Elevated Levels of Short-Chain Fatty Acids Induce T Cell-Mediated Ureteritis and Hydronephrosis
Park, Goergen, HogenEsch et al
J Immunol (2016) 196 (5), 2388-400 DOI: 10.4049/jimmunol.1502046
Cited by 166
AI Summary: In this study, OriGene’s Mouse Ifng (NM_008337) qPCR Primer Pair (MP200990) and Mouse Il17a (NM_010552) qPCR Primer Pair (MP205311) were used to measure gene expression of key inflammatory cytokines, helping to assess T cell-mediated inflammation in the development of SCFA-induced ureteritis and hydronephrosis.
FigureFigure
Showing 1-1 of 1 papers.
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