Isocitrate dehydrogenase (IDH1) Mouse Monoclonal Antibody [Clone ID: OTI3G9]
SKU
CF800406
Carrier-free (BSA/glycerol-free) IDH1 mouse monoclonal antibody, clone OTI3G9 (formerly 3G9)
$620.00
3 Days*
Specifications
| Product Data | |
| Clone Name | OTI3G9 |
|---|---|
| Application | IHC, Simple Western, WB |
| Recommended Dilution | WB 1:2000, IHC 1:150; Simple Western 1:20-1:50 |
| Reactivity | Dog, Human, Mouse, Rat |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Synthetic peptide around the R132H mutation region of the human IDH conjugated to KLH |
| Buffer | Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose) |
| Reconstitution Method | For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific) |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Ambient |
| Predicted Protein Size | 46.5 kDa |
| Gene Name | isocitrate dehydrogenase (NADP(+)) 1 |
| Database Link | |
| Background | Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. Each NADP(+)-dependent isozyme is a homodimer. The protein encoded by this gene is the NADP(+)-dependent isocitrate dehydrogenase found in the cytoplasm and peroxisomes. It contains the PTS-1 peroxisomal targeting signal sequence. The presence of this enzyme in peroxisomes suggests roles in the regeneration of NADPH for intraperoxisomal reductions, such as the conversion of 2, 4-dienoyl-CoAs to 3-enoyl-CoAs, as well as in peroxisomal reactions that consume 2-oxoglutarate, namely the alpha-hydroxylation of phytanic acid. The cytoplasmic enzyme serves a significant role in cytoplasmic NADPH production. provided by RefSeq, Jul 2008 |
| Synonyms | HEL-216; HEL-S-26; IDCD; IDH; IDP; IDPC; PICD |
| Reference Data | |
| Protein Categories | Cancer: Brain and CNS, Cancer: Haematopoietic and Lymphoid, Cardiovascular diseases, Intracellular Proteins |
| Protein Pathways | Citrate cycle (TCA cycle), Glutathione metabolism, Metabolic pathways |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other "OTI3G9" antibodies (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| TA800406 | IDH1 (Isocitrate Dehydrogenase 1) mouse monoclonal antibody, clone OTI3G9 (formerly 3G9) | 100 ul |
$447.00
|
|
| TA800406AM | IDH1 mouse monoclonal antibody,clone 3G9, Biotinylated | 100 ul |
$509.00
|
|
| TA800406BM | IDH1 mouse monoclonal antibody,clone 3G9, HRP conjugated | 100 ul |
$509.00
|
|
| TA800406S | IDH1 (Isocitrate Dehydrogenase 1) mouse monoclonal antibody, clone OTI3G9 (formerly 3G9) | 30 ul |
$200.00
|
|
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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