PMS2 Mouse Monoclonal Antibody [Clone ID: OTI4B7]
Specifications
| Product Data | |
| Clone Name | OTI4B7 |
|---|---|
| Application | IF, IHC, WB |
| Recommended Dilution | WB 1:500, IHC 1:150, IF: 1:100 |
| Reactivity | Human |
| Antibody Host | Mouse |
| Isotype | IgG2b |
| Clonality | Monoclonal |
| Immunogen | Full length human recombinant protein of human PMS2(NP_000526) produced in HEK293T cell. |
| Buffer | Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose) |
| Reconstitution Method | For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific) |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Ambient |
| Predicted Protein Size | 95.6 kDa |
| Gene Name | PMS1 homolog 2, mismatch repair system component |
| Database Link | |
| Background | This gene is one of the PMS2 gene family members found in clusters on chromosome 7. The product of this gene is involved in DNA mismatch repair. It forms a heterodimer with MLH1 and this complex interacts with other complexes bound to mismatched bases. Mutations in this gene are associated with hereditary nonpolyposis colorectal cancer, Turcot syndrome, and are a cause of supratentorial primitive neuroectodermal tumors. Alternatively spliced transcript variants have been observed for this gene. provided by RefSeq, Jul 2008 |
| Synonyms | HNPCC4; PMS2CL; PMSL2 |
| Reference Data | |
| Protein Categories | ADC Targets, Cancer: Gastrointestinal, Intracellular Proteins |
| Protein Families | Druggable Genome |
| Protein Pathways | Mismatch repair |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other "OTI4B7" antibodies (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| TA506683 | PMS2 mouse monoclonal antibody, clone OTI4B7 (formerly 4B7) | 100 ul |
$447.00
|
|
| TA506683AM | PMS2 mouse monoclonal antibody,clone 4B7, Biotinylated | 100 ul |
$509.00
|
|
| TA506683BM | PMS2 mouse monoclonal antibody,clone 4B7, HRP conjugated | 100 ul |
$509.00
|
|
| TA506683S | PMS2 mouse monoclonal antibody, clone OTI4B7 (formerly 4B7) | 30 ul |
$200.00
|
|
Citations
Related Products
- Price:
- Actual Price:
Welcome to OriGene AI!
I'm your AI-powered guide to everything OriGene.
Ask me anything:
- Product specs
- Ordering help
- Technical questions
- How to find exactly what your experiment needs
Prefer a live agent? Connect with us by clicking the green chat icon, as seen in the image below or email our team at custsupport@origene.com.