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CD45 (PTPRC) Mouse Monoclonal Antibody [Clone ID: OTI4C11]

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SKU
CF506567
Carrier-free (BSA/glycerol-free) PTPRC mouse monoclonal antibody, clone OTI4C11 (formerly 4C11)
Size:
100 ug
Formulation:
Carrier-free Standard
Conjugation:
Unconjugated
  $620.00
3 Days*
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View other "CD45 or NM_002838" antibodies

Specifications
Specifications
Product Data
Clone Name OTI4C11
Application IF, IHC, WB
Recommended Dilution WB 1:400~4000, IHC 1:500, IF 1:100
Reactivity Human
Antibody Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Full length human recombinant protein of human PTPRC(NP_002829) produced in HEK293T cell.
Buffer Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Ambient
Predicted Protein Size 147.1 kDa
Gene Name protein tyrosine phosphatase receptor type C
Database Link
Background The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Alternatively spliced transcripts variants of this gene, which encode distinct isoforms, have been reported. provided by RefSeq, Jun 2012
Synonyms B220; CD45; CD45R; GP180; L-CA; LCA; LY5; T200
Reference Data
Protein Categories ADC Targets, CD Markers, Cytokines, Growth Factors, Immune system diseases, Intracellular Proteins, Membrane Proteins
Protein Families Druggable Genome, ES Cell Differentiation/IPS, Phosphatase, Transmembrane
Protein Pathways Cell adhesion molecules (CAMs), Fc gamma R-mediated phagocytosis, Primary immunodeficiency, T cell receptor signaling pathway
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Other "OTI4C11" antibodies (4)
SKU Description Size Price
TA506567 PTPRC mouse monoclonal antibody, clone OTI4C11 (formerly 4C11) 100 ul
$447.00
TA506567AM PTPRC mouse monoclonal antibody,clone 4C11, Biotinylated 100 ul
$509.00
TA506567BM PTPRC mouse monoclonal antibody,clone 4C11, HRP conjugated 100 ul
$509.00
TA506567S PTPRC mouse monoclonal antibody, clone OTI4C11 (formerly 4C11) 30 ul
$200.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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