CD19 Mouse Monoclonal Antibody [Clone ID: OTI3B10]
SKU
CF506236
Carrier-free (BSA/glycerol-free) CD19 mouse monoclonal antibody, clone OTI3B10 (formerly 3B10)
$620.00
3 Days*
Specifications
| Product Data | |
| Clone Name | OTI3B10 |
|---|---|
| Application | FC, IF, IHC, WB |
| Recommended Dilution | WB 1:4000, IHC 1:150, IF 1:100 |
| Reactivity | Human |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Full length human recombinant protein of human CD19(NP_001761) produced in HEK293T cell. |
| Buffer | Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose) |
| Reconstitution Method | For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific) |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Ambient |
| Predicted Protein Size | 60.9 kDa |
| Gene Name | CD19 molecule |
| Database Link | |
| Background | Lymphocytes proliferate and differentiate in response to various concentrations of different antigens. The ability of the B cell to respond in a specific, yet sensitive manner to the various antigens is achieved with the use of low-affinity antigen receptors. This gene encodes a cell surface molecule which assembles with the antigen receptor of B lymphocytes in order to decrease the threshold for antigen receptor-dependent stimulation. provided by RefSeq, Jul 2008 |
| Synonyms | B4; CVID3 |
| Reference Data | |
| Protein Categories | ADC Targets, CAR-T Targets, CD Markers, Immune system diseases, Membrane Proteins |
| Protein Families | Druggable Genome, Transmembrane |
| Protein Pathways | B cell receptor signaling pathway, Hematopoietic cell lineage, Primary immunodeficiency |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other "OTI3B10" antibodies (6)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| TA506236 | CD19 mouse monoclonal antibody, clone OTI3B10 | 100 ul |
$447.00
|
|
| TA506236AM | CD19 mouse monoclonal antibody,clone 3B10, Biotinylated | 100 ul |
$509.00
|
|
| TA506236BM | CD19 mouse monoclonal antibody,clone 3B10, HRP conjugated | 100 ul |
$509.00
|
|
| TA506236DM | CD19 mouse monoclonal antibody,clone 3B10, DyLight 488 conjugated | 100 ul |
$509.00
|
|
| TA506236HM | CD19 mouse monoclonal antibody,clone 3B10, PE conjugated | 100 ul |
$509.00
|
|
| TA506236S | CD19 mouse monoclonal antibody, clone OTI3B10 | 30 ul |
$200.00
|
|
Citations
Mammalian Cell Membrane Hybrid Polymersomes for mRNA Delivery
Shin, Ahn, Kim et al
ACS Appl Mater Interfaces (2024)
Shin, Ahn, Kim et al
ACS Appl Mater Interfaces (2024)
Cited by 3
AI Summary: In this study, OriGene’s CD19 mouse monoclonal antibody (clone OTI3B10, TA506236) and CD47 mouse monoclonal antibody (clone B6H12.2, AM33292PU-S) were used to characterize and confirm the presence of specific membrane proteins on the hybrid polymersomes, supporting the evaluation of their antigenic surface properties.
Snippet: sis membrane (10 K) (Thermo Fisher Scientific, USA), Trans-Blot Turbo RTA Mini 0.2 μm nitrocellulose transfer kit (Bio-Rad, USA), CD19 mouse monoclonal antibody, clone OTI3B10, catalog no. TA506236 (Origene, USA, #F003), CD47 mouse monoclonal antibody, clone B6H12.2, catalog no. AM33292PU-S, purified (Origene, USA, #3P220803), recombinant HRP antisodium potassium ATPase antibody, clone EP1845Y (Abcam, United Kingdom, #ab185065), Goat antirabbit IgG H&L (horseradish peroxidase-conjugated) (Abcam, United Kingdom, #ab6721), Rabbit antimouse IgG H&L (horseradish peroxidase-conjugated, #ab6709) (Abcam, United Kingdom), EZ-cytox (DoGenBio, Republic of Korea), Hoechst 33342 (Thermo Fis
Recombinant Human CD19 in CHO-K1 Cells: Glycosylation Patterns as a Quality Attribute of High Yield Processes
Billerhart, Hunjadi, Hawlin et al
Int J Mol Sci (2023) 24 (13) DOI: 10.3390/ijms241310891
Billerhart, Hunjadi, Hawlin et al
Int J Mol Sci (2023) 24 (13) DOI: 10.3390/ijms241310891
Cited by 6
AI Summary: OriGene’s 3B10 anti-CD19 antibody (TA506236AM) was used in Bio-Layer Interferometry assays to evaluate the binding affinity of the recombinant CD19-AD2 protein, contributing to the assessment of protein quality in this study.
Snippet: D19 antibodies, including FMC63 (Ab00613-2.0, Absolute Antibody Ltd., Oxford, Oxfordshire, UK), HIB19 (302204, BioLegend, USA), 4G7 (Ab00219-1.1, Absolute Antibody Ltd.), as well as 3B10 (TA506236AM, Origene Tech. Inc., Rockville, MA, USA), was measured by Bio-Layer Interferometry (BLI). All measurements were performed at 25 °C on an Octet RED96 instrument (Sartorius, Göttingen, Lower Saxony, Ge
Induction of resistance to chimeric antigen receptor T cell therapy by transduction of a single leukemic B cell
Ruella, Xu, Barrett et al
Nat. Med. (2018) 24 (10), 1499-1503 DOI: 10.1038/s41591-018-0201-9
Ruella, Xu, Barrett et al
Nat. Med. (2018) 24 (10), 1499-1503 DOI: 10.1038/s41591-018-0201-9
AI Summary: OriGene's CD19-specific monoclonal antibody OTI3B10 (TA506236) was used to study CD19 protein expression by flow cytometry and confocal microscopy, helping to characterize the mechanism of resistance to CAR T cell therapy described in the paper.
Snippet: … In the terminology used in this manuscript, CART19 refers to all CAR T cell products directed against CD19, CTL019 refers to the Penn/ Novartis-developed murine CART19 product, and CAR19 refers to the chimeric antigen receptor itself. CD19 protein expression was studied by flow cytometry and confocal microscopy using the following CD19-specific monoclonal antibodies: OTI3B10 (Origene no. TA506236)
T cell receptor rearrangements in a patient with γ-heavy chain disease: A case report
Zhou, Chen, Zhang et al
Oncol Lett (2016) 11 (6), 4147-4151 DOI: 10.3892/ol.2016.4515
Zhou, Chen, Zhang et al
Oncol Lett (2016) 11 (6), 4147-4151 DOI: 10.3892/ol.2016.4515
AI Summary: OriGene products, specifically the Human IGHG1 (NM_001083.3) qPCR Primer Pair (HP208634) and Human TCRB (NM_001243.4) qPCR Primer Pair (HP209227), were used in this study to detect and analyze immunoglobulin heavy chain and T cell receptor gene rearrangements in patient tissue samples.
Showing 1-4 of 4 papers.
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