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ERG Mouse Monoclonal Antibody [Clone ID: OTI8A9]

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SKU
CF506201
Carrier-free (BSA/glycerol-free) ERG mouse monoclonal antibody, clone OTI8A9 (formerly 8A9)
Size:
100 ug
Formulation:
Carrier-free Standard
Conjugation:
Unconjugated
  $620.00
3 Days*
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View other "ERG or NM_182918" antibodies

Specifications
Specifications
Product Data
Clone Name OTI8A9
Application IF, IHC, WB
Recommended Dilution WB: 1:4000, IHC: 1:150, IF: 1:50-1:100
Reactivity Human, Mouse, Rat
Antibody Host Mouse
Isotype IgG2b
Clonality Monoclonal
Immunogen Full length human recombinant protein of human ERG(NP_891548) produced in HEK293T cell.
Buffer Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Ambient
Predicted Protein Size 53.7 kDa
Gene Name ETS transcription factor ERG
Database Link
Background This gene encodes a member of the erythroblast transformation-specific (ETS) family of transcriptions factors. All members of this family are key regulators of embryonic development, cell proliferation, differentiation, angiogenesis, inflammation, and apoptosis. The protein encoded by this gene is mainly expressed in the nucleus. It contains an ETS DNA-binding domain and a PNT (pointed) domain which is implicated in the self-association of chimeric oncoproteins. This protein is required for platelet adhesion to the subendothelium, inducing vascular cell remodeling. It also regulates hematopoesis, and the differentiation and maturation of megakaryocytic cells. This gene is involved in chromosomal translocations, resulting in different fusion gene products, such as TMPSSR2-ERG and NDRG1-ERG in prostate cancer, EWS-ERG in Ewing's sarcoma and FUS-ERG in acute myeloid leukemia. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jan
Synonyms erg-3; p55
Reference Data
Protein Categories Cancer: Sarcoma, Intracellular Proteins, Transciption Factors
Protein Families Druggable Genome, Transcription Factors
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Other "OTI8A9" antibodies (6)
SKU Description Size Price
TA506201 ERG mouse monoclonal antibody, clone OTI8A9 (formerly 8A9) 100 ul
$447.00
TA506201AM ERG mouse monoclonal antibody, clone OTI8A9 (formerly 8A9), Biotinylated 100 ul
$509.00
TA506201BM ERG mouse monoclonal antibody, clone OTI8A9 (formerly 8A9), HRP conjugated 100 ul
$509.00
TA506201S ERG mouse monoclonal antibody, clone OTI8A9 (formerly 8A9) 30 ul
$200.00
TA600177 ERG mouse monoclonal capture antibody, validated for ELISA and Luminex assays 100 ug
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TA700175 ERG biotinylated mouse monoclonal detection antibody, validated for ELISA and Luminex assays 50 ug
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file-alt Citations

A Co-opted Developmental Gene Regulatory Program in Endothelial Progenitors Promotes Tumor Angiogenic Phenotypes
Lee, Min, Park et al
Cancer Res (2026)
AI Summary: OriGene’s anti-ERG antibody (TA506201) was used in this study to identify and analyze endothelial cells, contributing to the characterization of tumor-associated endothelial cell phenotypes.
Snippet: AB_2049627), anti-ERG (1:50;OriGene, TA506201, RRID: AB_ 2623681), and anti-CDH5 (1:1,000;R&D Systems, AF938, RRID: AB_355726). The cells were incubated with proper secondary antibodies, including anti-mouse IgG Alexa Fluor 488 (Invitrogen, A-21202, RRID: AB_141607), anti-rabbit IgG Alexa Fluor 488 (Invitrogen, A-21206, RRID: AB_2535792), anti-mouse IgG Alexa
Showing 1-1 of 1 papers.
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