RIOK2 Mouse Monoclonal Antibody [Clone ID: OTI3E11]

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SKU
CF505140
Carrier-free (BSA/glycerol-free) RIOK2 mouse monoclonal antibody, clone OTI3E11 (formerly 3E11)
  $620.00
3 Days*
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Specifications
Specifications
Product Data
Clone Name OTI3E11
Application IF, IHC, Simple Western, WB
Recommended Dilution WB 1:500~4000, IHC 1:150, IF 1:100, Simple Western 1:20 - 1:50
Reactivity Human, Monkey, Mouse
Antibody Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Human recombinant protein fragment corresponding to amino acids 277-552 of human RIOK2(NP_060813) produced in E.coli.
Buffer Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Ambient
Predicted Protein Size 63.1 kDa
Gene Name RIO kinase 2
Database Link
Synonyms RIO2
Reference Data
Protein Categories Enzyme: Kinases, Intracellular Proteins
Protein Families Druggable Genome, Protein Kinase
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Other "OTI3E11" antibodies (4)
SKU Description Size Price
TA505140 RIOK2 mouse monoclonal antibody, clone OTI3E11 (formerly 3E11) 100 ul
$447.00
TA505140AM RIOK2 mouse monoclonal antibody,clone 3E11, Biotinylated 100 ul
$509.00
TA505140BM RIOK2 mouse monoclonal antibody,clone 3E11, HRP conjugated 100 ul
$509.00
TA505140S RIOK2 mouse monoclonal antibody, clone OTI3E11 (formerly 3E11) 30 ul
$200.00

file-alt Citations

RIOK2 transcriptionally regulates TRiC and dyskerin complexes to prevent telomere shortening
Ghosh, Nguyen, Choi et al
Nat Commun (2024) 15 (1), 7138 DOI: 10.1038/s41467-024-51336-3
Cited by 9
AI Summary: In this study, the OriGene RIOK2 mouse monoclonal antibody (OTI3E11, TA505140) was used to detect RIOK2 protein levels, supporting the investigation of RIOK2’s role in regulating telomere maintenance.
Snippet: resh blocking buffer at 4 °C for overnight (O/N): β-Actin rabbit polyclonal antibody at 1:1000 (3967 S, Cell Signaling Technology), RIOK2 mouse monoclonal antibody at 1:1000 (OTI3E11, TA505140, Origene), TCAB1 rabbit polyclonal antibody at 1:1000 (Novus Biologicals #NB100-68252). After O/N incubation, membranes were washed four times with PBST buffer for 5 min each on a rocker at RT, follo
FigureFigureFigure
WB
Identification of RIOK2 as a master regulator of human blood cell development
Ghosh, Raundhal, Myers et al
Nat Immunol (2022) 23 (1), 109-121 DOI: 10.1038/s41590-021-01079-w
Cited by 24
AI Summary: OriGene's RIOK2 mouse monoclonal antibody (OTI3E11, TA505140) was used in this study to detect RIOK2 protein levels, thereby enabling the investigation of RIOK2's role as a master regulator in human blood cell development.
Snippet: …Here we Save;β-actin rabbit polyclonal antibody at a dilution of 1:1,000 (3967S, Cell Signaling Technology) and RIOK2 mouse monoclonal antibody at a 1:1,000 dilution (OTI3E11, TA505140, Origene). …
WB
Identification of a small molecule that selectively inhibits ERG-positive cancer cell growth
Mohamed, Xavier, Sukumar et al
Cancer Res. (2018)
AI Summary: OriGene contributed to this study by providing the RIOK2 mouse monoclonal antibody (TA505140), which was used to investigate the role of RIOK2 in ERG-positive prostate cancer cell growth inhibition.
Snippet: purchased from Cell Signaling. anti-phospho-S6RP(cat.#2211), anti-S6RP(cat.# 2217) and anti-mTOR(cat.#2983) antibodies were also from Cell Signaling Technology. RIOK2 mouse monoclonal antibody (TA505140) was purchased from Origene. Sheep
Showing 1-3 of 3 papers.
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