Cbl c (CBLC) Mouse Monoclonal Antibody [Clone ID: OTI4E3]
SKU
CF505093
Carrier-free (BSA/glycerol-free) CBLC mouse monoclonal antibody, clone OTI4E3 (formerly 4E3)
$620.00
3 Days*
Specifications
| Product Data | |
| Clone Name | OTI4E3 |
|---|---|
| Application | FC, WB |
| Recommended Dilution | WB 1:500, FLOW 1:100 |
| Reactivity | Human |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 244-474 of human CBLC(NP_036248) produced in HEK293T cell. |
| Buffer | Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose) |
| Reconstitution Method | For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific) |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Ambient |
| Predicted Protein Size | 52.3 kDa |
| Gene Name | Cbl proto-oncogene C |
| Database Link | |
| Background | This gene encodes a member of the Cbl family of E3 ubiquitin ligases. Cbl proteins play important roles in cell signaling through the ubiquitination and subsequent downregulation of tyrosine kinases. Expression of this gene may be restricted to epithelial cells, and alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. provided by RefSeq, Feb 2012 |
| Synonyms | CBL-3; CBL-SL; RNF57 |
| Note | WB application: Only overexpression results are guaranteed, not endogenous |
| Reference Data | |
| Protein Categories | Growth Factors, Intracellular Proteins |
| Protein Families | Druggable Genome |
| Protein Pathways | Chronic myeloid leukemia, Endocytosis, ErbB signaling pathway, Insulin signaling pathway, Jak-STAT signaling pathway, Pathways in cancer, T cell receptor signaling pathway, Ubiquitin mediated proteolysis |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other "OTI4E3" antibodies (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| TA505093 | CBLC mouse monoclonal antibody, clone OTI4E3 (formerly 4E3) | 100 ul |
$447.00
|
|
| TA505093AM | CBLC mouse monoclonal antibody,clone 4E3, Biotinylated | 100 ul |
$509.00
|
|
| TA505093BM | CBLC mouse monoclonal antibody,clone 4E3, HRP conjugated | 100 ul |
$509.00
|
|
| TA505093S | CBLC mouse monoclonal antibody, clone OTI4E3 (formerly 4E3) | 30 ul |
$200.00
|
|
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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