Amyloid Precursor Protein (APP) Mouse Monoclonal Antibody [Clone ID: OTI7B8]
Specifications
| Product Data | |
| Clone Name | OTI7B8 |
|---|---|
| Application | IHC |
| Recommended Dilution | IHC 1:150 |
| Reactivity | Human, Mouse, Rat |
| Antibody Host | Mouse |
| Isotype | IgG2a |
| Clonality | Monoclonal |
| Immunogen | Full length human recombinant protein of human APP(NP_000475) produced in HEK293T cell. |
| Buffer | Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose) |
| Reconstitution Method | For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific) |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Ambient |
| Predicted Protein Size | 85.1 kDa |
| Gene Name | amyloid beta precursor protein |
| Database Link | |
| Background | This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene. provided by RefSeq |
| Synonyms | AAA; ABETA; ABPP; AD1; APPI; CTFgamma; CVAP; PN-II; PN2 |
| Reference Data | |
| Protein Categories | Chemokines, Growth Factors, Intracellular Proteins, Membrane Proteins, Nervous system: Neurodegenerative diseases, Secreated Proteins |
| Protein Families | Druggable Genome, Transmembrane |
| Protein Pathways | Alzheimer's disease |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other "OTI7B8" antibodies (11)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| CF500978 | Carrier-free (BSA/glycerol-free) APP mouse monoclonal antibody, clone OTI7B8 (formerly 7B8) | 100 ug |
$620.00
|
|
| TA500978 | Anti-APP (Amyloid beta precursor protein) mouse monoclonal antibody, clone OTI7B8 (formerly 7B8) | 100 ul |
$447.00
|
|
| TA500978AM | Anti-APP (Amyloid beta precursor protein) mouse monoclonal antibody, clone OTI7B8 (formerly 7B8), Biotinylated | 100 ul |
$509.00
|
|
| TA500978BM | Anti-APP (Amyloid beta precursor protein) mouse monoclonal antibody, clone OTI7B8 (formerly 7B8), HRP conjugated | 100 ul |
$509.00
|
|
| TA500978S | Anti-APP (Amyloid beta precursor protein) mouse monoclonal antibody, clone OTI7B8 (formerly 7B8) | 30 ul |
$200.00
|
|
| TA505055 | APP (Amyloid beta precursor protein) mouse monoclonal antibody, clone OTI7B8 (formerly 7B8) | 100 ul |
$447.00
|
|
| TA505055AM | APP mouse monoclonal antibody,clone 7B8, Biotinylated | 100 ul |
$509.00
|
|
| TA505055BM | APP mouse monoclonal antibody,clone 7B8, HRP conjugated | 100 ul |
$509.00
|
|
| TA505055S | APP (Amyloid beta precursor protein) mouse monoclonal antibody, clone OTI7B8 (formerly 7B8) | 30 ul |
$200.00
|
|
| TA600259 | APP mouse monoclonal capture antibody, validated for Luminex assays | 100 ug |
$458.00
|
|
| TA700259 | APP biotinylated mouse monoclonal detection antibody, validated for Luminex assays | 50 ug |
$494.00
|
|
Citations
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