ATIC Mouse Monoclonal Antibody [Clone ID: OTI1D2]
Specifications
| Product Data | |
| Clone Name | OTI1D2 |
|---|---|
| Application | FC, WB |
| Recommended Dilution | WB 1:500~2000, FLOW 1:100 |
| Reactivity | Dog, Human, Monkey, Mouse, Rat |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Full length human recombinant protein of human ATIC(NP_004035) produced in HEK293T cell. |
| Buffer | Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose) |
| Reconstitution Method | For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific) |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Ambient |
| Predicted Protein Size | 64.4 kDa |
| Gene Name | 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase |
| Database Link | |
| Background | This gene encodes a bifunctional protein that catalyzes the last two steps of the de novo purine biosynthetic pathway. The N-terminal domain has phosphoribosylaminoimidazolecarboxamide formyltransferase activity, and the C-terminal domain has IMP cyclohydrolase activity. A mutation in this gene results in AICA-ribosiduria. provided by RefSeq |
| Synonyms | AICAR; AICARFT; HEL-S-70p; IMPCHASE; PURH |
| Reference Data | |
| Protein Categories | Intracellular Proteins |
| Protein Families | Stem cell - Pluripotency |
| Protein Pathways | Metabolic pathways, One carbon pool by folate, Purine metabolism |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other "OTI1D2" antibodies (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| TA504553 | ATIC mouse monoclonal antibody, clone OTI1D2 (formerly 1D2) | 100 ul |
$447.00
|
|
| TA504553AM | ATIC mouse monoclonal antibody, clone OTI1D2 (formerly 1D2), Biotinylated | 100 ul |
$509.00
|
|
| TA504553BM | ATIC mouse monoclonal antibody, clone OTI1D2 (formerly 1D2), HRP conjugated | 100 ul |
$509.00
|
|
| TA504553S | ATIC mouse monoclonal antibody, clone OTI1D2 (formerly 1D2) | 30 ul |
$200.00
|
|
Citations
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