SH2D2A Mouse Monoclonal Antibody [Clone ID: OTI3C7]
SKU
CF504372
Carrier-free (BSA/glycerol-free) SH2D2A mouse monoclonal antibody, clone OTI3C7 (formerly 3C7)
$620.00
3 Days*
Specifications
| Product Data | |
| Clone Name | OTI3C7 |
|---|---|
| Application | FC, IF, IHC, WB |
| Recommended Dilution | WB 1:500~2000, IF 1:100, FLOW 1:100 |
| Reactivity | Human, Monkey, Mouse |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Full length human recombinant protein of human SH2D2A(NP_003966) produced in HEK293T cell. |
| Buffer | Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose) |
| Reconstitution Method | For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific) |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Ambient |
| Predicted Protein Size | 42.8 kDa |
| Gene Name | SH2 domain containing 2A |
| Database Link | |
| Background | This gene encodes an adaptor protein thought to function in T-cell signal transduction. A related protein in mouse is responsible for the activation of lymphocyte-specific protein-tyrosine kinase and functions in downstream signaling. Alternative splicing results in multiple transcript variants. provided by RefSeq |
| Synonyms | F2771; SCAP; TSAD; VRAP |
| Reference Data | |
| Protein Categories | Intracellular Proteins |
| Protein Pathways | VEGF signaling pathway |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other "OTI3C7" antibodies (5)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| TA400030 | Anti-SH2D2A mouse mAb, clone OTI3C7, DyLight488 conjugated | 100 ul |
$495.00
|
|
| TA504372 | SH2D2A mouse monoclonal antibody, clone OTI3C7 (formerly 3C7) | 100 ul |
$447.00
|
|
| TA504372AM | SH2D2A mouse monoclonal antibody,clone 3C7, Biotinylated | 100 ul |
$509.00
|
|
| TA504372BM | SH2D2A mouse monoclonal antibody,clone 3C7, HRP conjugated | 100 ul |
$509.00
|
|
| TA504372S | SH2D2A mouse monoclonal antibody, clone OTI3C7 (formerly 3C7) | 30 ul |
$200.00
|
|
Citations
Polarity of CD4+ T cells towards the antigen presenting cell is regulated by the Lck adapter TSAd
Abrahamsen, Sundvold-Gjerstad, Habtamu et al
Sci Rep (2018) 8 (1), 13319 DOI: 10.1038/s41598-018-31510-6
Abrahamsen, Sundvold-Gjerstad, Habtamu et al
Sci Rep (2018) 8 (1), 13319 DOI: 10.1038/s41598-018-31510-6
AI Summary: OriGene’s anti-TSAd-DyLight 488 antibody (clone OTI3C7) was used in this study to detect and analyze TSAd protein expression, contributing to the investigation of how TSAd regulates CD4+ T cell polarization towards antigen presenting cells.
Snippet: ntibodies and reagents Antibodies used were anti-human CD3ε (OKT3, American Type Culture collection, Manassas, VA), anti-CD28 (clone CD28.2, BD Biosciences), and anti-TSAd-DyLight 488 (clone OTI3C7, Origene), anti–IL-4 (11B11, Bio X Cell), anti-IFNγ-FITC, anti-CD4-PerCP-Cy5.5 (RM4–5) and anti-CD44-FITC (KM201, BD), anti-CD62L-PE (MEL-14, Southern Biotech), anti-γ–tubulin (GTU-88, Sigma) a
Expression of the T-cell specific adapter protein in human tissues
Pandya, Leergaard, Dissen et al
Scand. J. Immunol. (2014)
Pandya, Leergaard, Dissen et al
Scand. J. Immunol. (2014)
Cited by 5
AI Summary: OriGene contributed to this study by providing the anti-human TSAd monoclonal antibodies (clones 4F3 and 3C7), which were used to detect and map TSAd protein expression in human tissues.
Snippet: 70%). Antibodies and reagents Primary antibodies used were anti-human TSAd (murine mAb clones 4F3 and 3C7, Origene, Rockville, MD, USA) and anti-CD3 (rabbit polyclonal Ab F7.2.38, Dako, Glostrup, Denmark). Secondary ... Cite SaveSaving
Showing 1-2 of 2 papers.
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complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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