PFKP Mouse Monoclonal Antibody [Clone ID: OTI3A12]
Specifications
| Product Data | |
| Clone Name | OTI3A12 |
|---|---|
| Application | FC, IF, IHC, WB |
| Recommended Dilution | WB 1:500~2000, IHC 1:150, IF 1:100, FLOW 1:100 |
| Reactivity | Human, Mouse, Rat |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Full length human recombinant protein of human PFKP(NP_002618) produced in HEK293T cell. |
| Buffer | Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose) |
| Reconstitution Method | For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific) |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Ambient |
| Predicted Protein Size | 85.4 kDa |
| Gene Name | phosphofructokinase, platelet |
| Database Link | |
| Background | The PFKP gene encodes the platelet isoform of phosphofructokinase (PFK) (ATP:D-fructose-6-phosphate-1-phosphotransferase, EC 2.7.1.11). PFK catalyzes the irreversible conversion of fructose-6-phosphate to fructose-1,6-bisphosphate and is a key regulatory enzyme in glycolysis. The PFKP gene, which maps to chromosome 10p, is also expressed in fibroblasts. See also the muscle (PFKM; MIM 610681) and liver (PFKL; MIM 171860) isoforms of phosphofructokinase, which map to chromosomes 12q13 and 21q22, respectively. Vora (1981) PubMed 6451249 determined that full tetrameric phophofructokinase enzyme expressed in platelets can be composed of subunits P4, P3L, and P2L2. supplied by OMIM |
| Synonyms | ATP-PFK; PFK-C; PFK-P; PFKF |
| Reference Data | |
| Protein Categories | Intracellular Proteins |
| Protein Families | Druggable Genome |
| Protein Pathways | Fructose and mannose metabolism, Galactose metabolism, Glycolysis / Gluconeogenesis, Metabolic pathways, Pentose phosphate pathway |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other "OTI3A12" antibodies (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| TA503980 | PFKP mouse monoclonal antibody, clone OTI3A12 (formerly 3A12) | 100 ul |
$447.00
|
|
| TA503980AM | PFKP mouse monoclonal antibody, clone OTI3A12 (formerly 3A12), Biotinylated | 100 ul |
$509.00
|
|
| TA503980BM | PFKP mouse monoclonal antibody, clone OTI3A12 (formerly 3A12), HRP conjugated | 100 ul |
$509.00
|
|
| TA503980S | PFKP mouse monoclonal antibody, clone OTI3A12 (formerly 3A12) | 30 ul |
$200.00
|
|
Citations
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